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Cetylpyridinium
go.drugbank.com/drugs/DB11073ApprovedInvestigationalCetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. … Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays.
Mixtures: Kank-A, NORAVER P TABLETAS DE DISOLUCIÓN BUCALCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingVascular endothelial growth factor A, long form
go.drugbank.com/bio_entities/BE0000163TargetHumansParticipates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed:35455969). Involved in protecting cells from hypoxia-mediated cell death (By similarity)
Polypeptides: Vascular endothelial growth factor A, long form3-hydroxy-3-methylglutaryl-coenzyme A reductase
go.drugbank.com/bio_entities/BE0001856TargetPseudomonas mevaloniiP.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductaseATP synthase F(0) complex subunit a
go.drugbank.com/bio_entities/BE0009014TargetHumansThese two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).
Polypeptides: ATP synthase F(0) complex subunit aSynonyms: Proton-conducting channel, ATP synthase F(0) complex subunit aV-type proton ATPase catalytic subunit A
go.drugbank.com/bio_entities/BE0009200TargetPlasmodium falciparum (isolate 3D7)Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates … V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular
Polypeptides: V-type proton ATPase catalytic subunit ASynonyms: V-ATPase subunit ALipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Mixtures: VitaHealth L-Glutathione Plus, Protect Cardio AFCategories: Compounds used in a research, industrial, or household setting, Vitamin B ComplexRanitidine
go.drugbank.com/drugs/DB00863ApprovedWithdrawnRanitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine]. … [A176843] Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of gastric acid associated conditions and is therefore widely used in GERD and other gastric-acid related
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: SAMPEP TABLETAS DE 150 MG, RANITIDIN AL 150Hyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigational[A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties. … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.
Mixtures: Uro-L, Urin D/SSynonyms: L-Hyoscyamine, L-Tropine tropateTerbinafine
go.drugbank.com/drugs/DB00857ApprovedInvestigationalVet approvedTerbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. … [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall
Mixtures: Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%, Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersGemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalGemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. … [A233135] Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesSynonyms: 2'-Deoxy-2',2'-difluorocytidine, 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one