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Intracellular exo-alpha-(1->5)-L-arabinofuranosidase
go.drugbank.com/bio_entities/BE0001766TargetGeobacillus stearothermophilusCatalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans).
Polypeptides: Intracellular exo-alpha-(1->5)-L-arabinofuranosidaseSynonyms: Intracellular arabinan exo-alpha-(1->5)-L-arabinosidaseNAD-dependent protein deacylase sirtuin-5, mitochondrial
go.drugbank.com/bio_entities/BE0003362TargetHumansNAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693, PubMed:29180469). Activates CPS1 an...
Polypeptides: NAD-dependent protein deacylase sirtuin-5, mitochondrialSynonyms: SIR2-like protein 5, Regulatory protein SIR2 homolog 53-oxo-5-alpha-steroid 4-dehydrogenase
go.drugbank.com/bio_entities/BE0004887EnzymeTargetHumansAlso able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT) (PubMed:17986282, PubMed:26855069) … Catalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 2, 3-oxo-5-alpha-steroid 4-dehydrogenase 1Synonyms: Steroid 5-alpha-reductase 2, Steroid 5-alpha-reductase 2-likeVery long chain fatty acid elongase 5
go.drugbank.com/bio_entities/BE0009375EnzymeTargetHumansThis endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle.
Polypeptides: Very long chain fatty acid elongase 5Synonyms: ELOVL FA elongase 5, ELOVL fatty acid elongase 5Mitogen-activated protein kinase kinase kinase 5
go.drugbank.com/bio_entities/BE0018876TargetHumansSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determ...
Polypeptides: Mitogen-activated protein kinase kinase kinase 5Synonyms: MEKK 5, MEK kinase 5T cell receptor beta variable 5-6
go.drugbank.com/bio_entities/BE0023691TargetHumansV region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and ...
Polypeptides: T cell receptor beta variable 5-6Naftifine
go.drugbank.com/drugs/DB00735ApprovedNaftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum
International brands: A MeiProducts: DERMİFİN FORTE %2 JEL, 30 G, Dermifin Forte %2 Krem, 30 GClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigational[L905] Due to its severe adverse effects profile, clozapine is only available through a restricted program under a Risk Evaluation Mitigation Strategy (REMS) called the Clozapine REMS Program.[L905] … [A256713,A256718] However, continued evidence of its effectiveness led to clozapine's eventual reintroduction, although with a reluctance to prescribe it.
Categories: Dopamine D2 Receptor Antagonists, Serotonin 5-HT1 Receptor AntagonistsProducts: CLONEX 25 MG TABLET, 50 ADET, LEPONEX 25 MG TABLET, 50 ADETNarcolepsy Without Cataplexy
go.drugbank.com/conditions/DBCOND0048179Drugs: PitolisantSynonyms: Narcolepsy Type 2, Narcolepsy Type 2 (NT2)Calcipotriol
go.drugbank.com/drugs/DB02300ApprovedInvestigationalCalcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Mixtures: Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2%, DAIVOBET® GEL 50 MCG + 0.5 MG/ GCategories: Vitamin D and Analogues