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Displaying results 5721 - 5730 of 8696 in total
  1. Drug

    Pipequaline

    go.drugbank.com/drugs/DB13991
    Experimental

    Pipequaline has a similar pharmacological profile to the reported for the benzodiazepines. … Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed.

  2. Drug

    Lomifylline

    go.drugbank.com/drugs/DB18002
    Approved

    Categories: Drugs for Obstructive Airway Diseases
  3. Drug

    Inecalcitol

    go.drugbank.com/drugs/DB04796
    Investigational

  4. Drug

    Phenprocoumon

    go.drugbank.com/drugs/DB00946
    ApprovedInvestigationalWithdrawn

    Coumarin derivative that acts as a long-acting oral anticoagulant.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  5. Drug

    V24343

    go.drugbank.com/drugs/DB05201
    Investigational

    The anti-obesity drug, V24343, acts by targeting the CB1 receptor in the brain and suppressing a person's appetite.

  6. Drug

    Quisovalimab

    go.drugbank.com/drugs/DB16482
    Investigational

    Categories: Experimental Unapproved Treatments for COVID-19
  7. Drug

    Tenofovir

    go.drugbank.com/drugs/DB14126
    Investigational

    Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. … [A37693] In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog.

    Categories: P-glycoprotein substrates
  8. Target

    Vitamin B12 transporter BtuB

    go.drugbank.com/bio_entities/BE0001470
    TargetTransporterEscherichia coli (strain K12)

    Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space (PubMed:4579869). It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.

    Synonyms: Cobalamin receptor
  9. Target

    Neuropilin-1

    go.drugbank.com/bio_entities/BE0002129
    TargetHumans

    Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system.

    Synonyms: Vascular endothelial cell growth factor 165 receptor
  10. Target

    T-cell surface glycoprotein CD3 zeta chain

    go.drugbank.com/bio_entities/BE0003458
    TargetHumans

    When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z.

    Synonyms: T-cell receptor T3 zeta chain