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Displaying results 5731 - 5740 of 10000 in total
  1. Drug

    (1R)-1-(2-thienylacetylamino)-1-phenylmethylboronic acid

    go.drugbank.com/drugs/DB08552
    Experimental

    This compound belongs to the benzenes and substituted derivatives. These are aromatic compounds containing at least one benzene ring. This medication targets the protein beta-lactamase.

  2. Drug

    R411

    go.drugbank.com/drugs/DB05468
    Experimental

    R411 is a non-steroid oral medicine for the treatment of asthma. It is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation. … It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to either a4b1 or a4b7.

  3. Drug

    SCIB1

    go.drugbank.com/drugs/DB18439
    Investigational

    It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate the patient's T cells to have a stronger reaction against melanoma cells. … It is being investigated for the treatment of melanoma.

  4. Drug

    Carbon black

    go.drugbank.com/drugs/DB11980
    Investigational

    [A263401] Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and has been linked to carcinogenicity.[A263406, A263411, A263416] … Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment [A263396] with demonstrated adverse effects on pulmonary function.

    Synonyms: VEGETABLE CARBON (E 153)
  5. Drug

    Antipain

    go.drugbank.com/drugs/DB15251
    Experimental

    [A214490] The binding of antipain to OPB has been used in molecular dynamic studies to identify other OPB inhibitors with more favourable pharmacodynamic and pharmacokinetic properties for potential development … [A214481] Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells or those treated with chemical mutagens such as _N_-methyl-_N_'-nitro

  6. Drug

    Covax-19™

    go.drugbank.com/drugs/DB15846
    Investigational

    Covax-19™ was tested in animal studies, and shown to achieve potent antibody and T-cell responses against the COVID-19 spike protein. … As of June 2020, the vaccine is in Phase 1 trials to evaluate safety and immune responses (NCT04428073).

  7. Drug

    Insulin beef

    go.drugbank.com/drugs/DB09456
    Approved

    Insulin beef has been discontinued in the US and Canada since 2017.[L10827]

  8. Drug

    Oxatomide

    go.drugbank.com/drugs/DB12877
    Approved

    Oxatomide has been used in trials studying the treatment of Muscular Dystrophy, Duchenne.

  9. Drug

    ME-344

    go.drugbank.com/drugs/DB13062
    Investigational

    ME-344 has been used in trials studying the treatment of Solid Tumors.

  10. Drug

    Parthenolide

    go.drugbank.com/drugs/DB13063
    ApprovedInvestigational

    Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis.