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Displaying results 5731 - 5740 of 8696 in total
  1. Target

    Neuropilin-2

    go.drugbank.com/bio_entities/BE0010030
    TargetHumans

    High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF

    Synonyms: Vascular endothelial cell growth factor 165 receptor 2
  2. Drug

    Cerulenin

    go.drugbank.com/drugs/DB01034
    Experimental

    Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols.

  3. Drug

    FT516

    go.drugbank.com/drugs/DB15732
    Investigational

    It is also a potential therapy for COVID-19. … This compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation.

  4. Drug

    Pentaglobin

    go.drugbank.com/drugs/DB15865
    Investigational

    Pentaglobin, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin preparations. It is comprised of immunoglobulin G (IgG) (https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A (IgA) while als...

  5. Drug

    V24343

    go.drugbank.com/drugs/DB05201
    Investigational

    The anti-obesity drug, V24343, acts by targeting the CB1 receptor in the brain and suppressing a person's appetite.

  6. Target

    CD44 antigen

    go.drugbank.com/bio_entities/BE0001113
    TargetHumans

    Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment (PubMed:16541107, PubMed:19703720 … components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor

    Synonyms: Hyaluronate receptor, Extracellular matrix receptor IIIFunction: cargo receptor activity
  7. Target

    Small ribosomal subunit protein uS2

    go.drugbank.com/bio_entities/BE0002402
    TargetHumans

    May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA … Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.

    Synonyms: Laminin receptor 1, 67 kDa laminin receptor
  8. Drug

    5-fluorouridine

    go.drugbank.com/drugs/DB01629
    Investigational

    5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid.

    Synonyms: 5-Fur
  9. Drug

    Gadodiamide

    go.drugbank.com/drugs/DB00225
    ApprovedInvestigational

    [A263101] However, since linear, non-ionic GBCA is less stable than macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and thus more likely to cause side

  10. Drug

    DCLL-9718S

    go.drugbank.com/drugs/DB17392
    Investigational

    DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). … NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for