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Iptacopan
go.drugbank.com/drugs/DB16200ApprovedInvestigational[A262581] On December 6th, 2023, Iptacopan under the brand name Fabhalta was approved by the FDA for the treatment of adults with PNH. … Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor
Gadoteric acid
go.drugbank.com/drugs/DB09132ApprovedInvestigational[A263141,A263106] Gadoterate is approved by the FDA under the brand name DOTAREM on 20th March 2013 for intravenous uses with magnetic resonance imaging (MRI) in the brain (intracranial), spine, and
Omega-3-carboxylic acids
go.drugbank.com/drugs/DB09568ApprovedWithdrawnThe increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as opposed to other products whose form is as ethyl esters. … The rest of the concentration is represented by docosapentaenoic acid and traces of some other components such as alpha-tocopherol, gelatin, glycerol, sorbitol and purified water.
Norepinephrine
go.drugbank.com/drugs/DB00368ApprovedInvestigationalIt is also found in plants and is used pharmacologically as a sympathomimetic.
Glycerin
go.drugbank.com/drugs/DB09462ApprovedInvestigationalA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Mixtures: Select Brand Hemorrhoid, An12 Anus Premium CleanserSulfamethazine
go.drugbank.com/drugs/DB01582ApprovedVet approvedWithdrawnA sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
Mixtures: Trisulfaminic SusProcaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approvedProcaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].
Hydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect. … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus
Hexylcaine
go.drugbank.com/drugs/DB00473ApprovedWithdrawnHexylcaine has been discontinued in the US market. … Hexylcaine hydrochloride is also known as cyclaine and osmocaine. It is a short acting local anesthetic that acts through inhibition of sodium channels.
Moxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnAs well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome. … It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive.
Products: MOXONIDINA MYLAN GENERICS