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Displaying results 5831 - 5840 of 10000 in total
  1. Target

    Elongation factor 2

    go.drugbank.com/bio_entities/BE0009168
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: Elongation factor 2
  2. Target

    2-Cys peroxiredoxin

    go.drugbank.com/bio_entities/BE0009251
    TargetPlasmodium falciparum (isolate 3D7)

    Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

    Polypeptides: 2-Cys peroxiredoxinSynonyms: 2-Cys Prx
  3. Target

    Nucleoside transporter 2

    go.drugbank.com/bio_entities/BE0009258
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: Nucleoside transporter 2
  4. Target

    P2X purinoceptor 2

    go.drugbank.com/bio_entities/BE0009820
    TargetHumans

    ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:10570044, PubMed:31636190). Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic r...

    Polypeptides: P2X purinoceptor 2
  5. Target

    NADPH oxidase 2

    go.drugbank.com/bio_entities/BE0009985
    TargetHumans

    Catalytic subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)) (PubMed:15338276, PubMed:36241643, PubMed:36413210, PubMed:38355798). In ...

    Polypeptides: NADPH oxidase 2
  6. Target

    Sphingomyelin phosphodiesterase 2

    go.drugbank.com/bio_entities/BE0012101
    TargetHumans

    Also hydrolyzes 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) in vivo (PubMed:10608884). … Also acts on 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and sphingosylphosphocholine (PubMed:10608884, PubMed:14741383)

    Polypeptides: Sphingomyelin phosphodiesterase 2
  7. Target

    Phosphatidylcholine:ceramide cholinephosphotransferase 2

    go.drugbank.com/bio_entities/BE0017188
    TargetEnzymeHumans

    Sphingomyelin synthase that primarily contributes to sphingomyelin synthesis and homeostasis at the plasma membrane. Catalyzes the reversible transfer of phosphocholine moiety in sphingomyelin biosynthesis: in the forward reaction transf...

    Polypeptides: Phosphatidylcholine:ceramide cholinephosphotransferase 2Synonyms: Sphingomyelin synthase 2
  8. Target

    Relaxin receptor 2

    go.drugbank.com/bio_entities/BE0017729
    TargetHumans

    Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3)

    Polypeptides: Relaxin receptor 2Synonyms: Relaxin family peptide receptor 2
  9. Target

    Protein argonaute-2

    go.drugbank.com/bio_entities/BE0020979
    TargetHumans

    Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide R...

    Polypeptides: Protein argonaute-2Synonyms: eIF2C 2, eIF-2C 2
  10. Drug

    Clopidogrel

    go.drugbank.com/drugs/DB00758
    ApprovedInvestigational

    Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. … L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI

    Mixtures: ATELIT-DUO® 75/100 MG TABLETAS, KLOGEL-A 75/75 MG KAPSUL, 30 ADETCategories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates