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Iodoform
go.drugbank.com/drugs/DB13813ApprovedInvestigationalVet approvedWithdrawnIodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. … It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions [A32890].
Hexylresorcinol
go.drugbank.com/drugs/DB11254ApprovedHexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. … The compound may also be used commonly in various commercial cosmetic anti-aging creams while ongoing studies research the possibility of using hexylresorcinol as an anti-cancer therapy - indications all
Mecobalamin
go.drugbank.com/drugs/DB03614ApprovedInvestigationalMixtures: L-Methyl MC NAC, L-Methyl-MC-NACProducts: N-cobal 0.5mg film-coated tabletPariglasgene brecaparvovec
go.drugbank.com/drugs/DB16801ApprovedPariglasgene brecaparvovec-opnr is an adeno-associated virus serotype 8 (AAV8)–based gene therapy for glycogen storage disease type Ia (GSDIa), a disorder caused by deficiency of the enzyme glucose-6-phosphatase … [L64050,L64051] It is administered as a single, one-time intravenous infusion.
Chlordiazepoxide
go.drugbank.com/drugs/DB00475ApprovedIllicitAn anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Mixtures: Nu-chlorax Capsules USP, AA PHARMA CHLORAX CAPSULEDolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigational[A7514] The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. … Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI).
Enzacamene
go.drugbank.com/drugs/DB11219ApprovedCommonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. … While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and cosmetic products is approved by Health Canada.
Mixtures: Secret Key Natural Cc Cushion Spf50 Pa / 02 Natural CcDebrisoquine
go.drugbank.com/drugs/DB04840ApprovedAn adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. … They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Inotersen
go.drugbank.com/drugs/DB14713ApprovedInvestigationalInotersen is a transthyretin-directed antisense oligonucleotide for the treatment of the polyneuropathy caused by hereditary transthyretin-mediated amyloidosis in adults.
Categories: DNA, Antisense, Decreased RNA IntegrityEnasidenib
go.drugbank.com/drugs/DB13874ApprovedInvestigationalThis small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and it also has shown to block several other enzymes that play a role in abnormal cell differentiation. … gene, which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345].
Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, UGT1A3 Substrates with a Narrow Therapeutic Index