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Displaying results 51 - 60 of 470 in total
  1. Target

    Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

    go.drugbank.com/bio_entities/BE0018277
    TargetHumans

    Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). … Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity)

    Polypeptides: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1Synonyms: Leucine-rich repeat and immunoglobulin domain-containing protein 1
  2. Target

    Acid ceramidase

    go.drugbank.com/bio_entities/BE0010906
    TargetHumans

    Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatty acids and sphingosine (PubMed:12764132, PubMed:12815059). … Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (PubMed:10610716, PubMed:11451951, PubMed:15655246, PubMed:26898341, PubMed:36752535, PubMed

    Polypeptides: Acid ceramidaseSynonyms: Acid CDase
  3. Target

    Iduronic acid

    go.drugbank.com/bio_entities/BE0004822
    TargetHumans

  4. Target

    Uric acid

    go.drugbank.com/bio_entities/BE0004823
    TargetHumans

  5. Target

    Hyaluronic acid

    go.drugbank.com/bio_entities/BE0009857
    TargetHumans and other mammals

  6. Target

    Fatty acid

    go.drugbank.com/bio_entities/BE0009632
    Target

  7. Target

    Bile acid-CoA:amino acid N-acyltransferase

    go.drugbank.com/bio_entities/BE0002303
    TargetEnzymeHumans

    In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs (PubMed:12810727) … Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine (PubMed:12239217, PubMed:12810727, PubMed:2037576, PubMed:8034703).

    Polypeptides: Bile acid-CoA:amino acid N-acyltransferaseSynonyms: Bile acid-CoA thioesterase
  8. Target

    Fatty acid synthase

    go.drugbank.com/bio_entities/BE0000959
    TargetEnzymeHumans

    Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. … This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain

    Polypeptides: Fatty acid synthaseSynonyms: Type I fatty acid synthase
  9. Target

    Fatty-acid peroxygenase

    go.drugbank.com/bio_entities/BE0001960
    TargetEnzymeBacillus subtilis (strain 168)

    Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide.

    Polypeptides: Fatty-acid peroxygenaseSynonyms: Fatty acid beta-hydroxylase
  10. Target

    Lysosomal acid glucosylceramidase

    go.drugbank.com/bio_entities/BE0000978
    TargetEnzymeHumans

    Plays a central role in the degradation of complex lipids and the turnover of cellular membranes (PubMed:27378698). … Can also hydrolyze cholesteryl 3-beta-D-glucoside producing glucose and cholesterol (PubMed:24211208, PubMed:26724485, PubMed:39395789).

    Polypeptides: Lysosomal acid glucosylceramidaseSynonyms: Acid beta-glucosidase, Lysosomal acid GCase