Search

Displaying results 51 - 60 of 10648 in total
  1. Drug

    Minocycline

    go.drugbank.com/drugs/DB01017
    ApprovedInvestigational

    [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria.

    Products: Ava-minocycline, AA-Minocycline 50mg Capsule
  2. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    greater potency than the R-enantiomer, but is metabolized at a higher rate. … [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer, each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Verelan PM, Verapamil Hydrochloride PM
  3. Indication

    Block, Heart

    go.drugbank.com/conditions/DBCOND0164920
    Drugs: Hyoscyamine
    Synonyms: AV Block, AV block (NOS)
  4. Drug

    Perindopril

    go.drugbank.com/drugs/DB00790
    ApprovedInvestigational

    ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). … Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.

    Mixtures: Ag-perindopril / Indapamide, Ag-perindopril / IndapamideProducts: PERINDOPRIL ERB 1A PH 4MG, COVEREX-AS
  5. Drug

    Glycerin

    go.drugbank.com/drugs/DB09462
    ApprovedInvestigational

    A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

    Mixtures: P3 Ai, P3 AiCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP2E1 Inducers
  6. Drug

    Alteplase

    go.drugbank.com/drugs/DB00009
    ApprovedInvestigational

    Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. … [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells.

    Mixtures: Activase RT-PA, Lysatec RT - PaSynonyms: t-PA, rt-PA
  7. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.

    Categories: P-glycoprotein substrates, Monoamine Oxidase A SubstratesProducts: Ava-sumatriptan, Ag-sumatriptan
  8. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death. … Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.

    Mixtures: Sentrazolam AMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Flecainide

    go.drugbank.com/drugs/DB01195
    ApprovedInvestigationalWithdrawn

    [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: Ag-flecainide, FLECAINIDACETAT AL 50MG
  10. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.

    Mixtures: DORZOLAMID AL COMP ATR, DORZOLAMID AL COMP ATRCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates