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Displaying results 51 - 60 of 10000 in total
  1. Drug

    Estriol

    go.drugbank.com/drugs/DB04573
    ApprovedInvestigationalVet approved

    A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. … It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the treatment of post-menopausal hot flashes.

    Synonyms: (16α,17β)-estra-1,3,5(10)-triene-3,16,17-triol, 1,3,5(10)-Estratriene-3,16-alpha,17beta-triolInternational brands: Synapause E
  2. Drug

    Promazine

    go.drugbank.com/drugs/DB00420
    ApprovedVet approvedWithdrawn

    A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. … It is currently not approved for use in the United States.

    Synonyms: N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine, 10-(3-(Dimethylamino)propyl)phenothiazineCategories: Adrenergic alpha-1 Receptor Antagonists, Serotonin 5-HT2 Receptor Antagonists
  3. Drug

    ADL 10-0101

    go.drugbank.com/drugs/DB05443
    Experimental

    ADL 10-0101 is a peripheral kappa opioid agonist analgesic product candidate. … Because ADL 10-0101 does not cross the blood-brain barrier and enter the brain when administered at therapeutic doses, it is expected to avoid central nervous system side effects.

  4. Drug

    Lacticaseibacillus rhamnosus

    go.drugbank.com/drugs/DB19282
    ApprovedInvestigational

    Synonyms: Lactobacillus rhamnosus (hansen, 1968) collins et al., 1989Mixtures: Fermalac Ecc 1b
  5. Drug

    Thioridazine

    go.drugbank.com/drugs/DB00679
    ApprovedWithdrawn

    Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618). … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity.

    Synonyms: 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine, 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazineInternational brands: Mellaril-S
  6. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs). … Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain.

    Synonyms: 17-β estradiol, (17β)-estra-1,3,5(10)-triene-3,17-diolInternational brands: Estraderm MX
  7. Drug

    Mesoridazine

    go.drugbank.com/drugs/DB00933
    ApprovedWithdrawn

    A phenothiazine antipsychotic with effects similar to chlorpromazine.

    Synonyms: 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylsulfinyl phenothiazine, 2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazineCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor Antagonists
  8. Drug

    Fluorouracil

    go.drugbank.com/drugs/DB00544
    ApprovedInvestigational

    A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.

    Synonyms: 5 FU, 5-FUMixtures: Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der Haut, VERRUTOL %0,5 + %10 DERİ ÇÖZELTİSİ (15 G)
  9. Drug

    (R)-tacrine(10)-hupyridone

    go.drugbank.com/drugs/DB04614
    Experimental

    Synonyms: (R)-tacrine(10)-hupyridone
  10. Drug

    Estrone

    go.drugbank.com/drugs/DB00655
    Approved

    Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. … Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase.

    Synonyms: 3-Hydroxy-1,3,5(10)-estratrien-17-oneCategories: 17-Ketosteroids, P-glycoprotein inducers