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Azithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalAzithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175]. … In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine].
Categories: cefixime and azithromycin, azithromycin, fluconazole and secnidazoleProducts: Zithromax Cap 250mg, ZITHROMAX TR-SAFT K B 25KGCarbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnIt was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies. … The compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued.
Categories: Compounds used in a research, industrial, or household settingProducts: LIQUIGEL UD 2.5MG/G EINZELMemantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalInitially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … Almost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and to 115 million by 2050 [F4366].
Mixtures: Memantine and Donepezil, Memantine and DonepezilCategories: donepezil and memantine, donepezil, memantine and Ginkgo foliumFatty Acid Elongation in Mitochondria
smpdb.ca/view/SMP0000054MetabolicIn liver and kidney fatty acid elongation operates best in the presence of both NADH and NADPH, whereas in heart and skeletal muscle, only NADH is required. … All of the fatty acids needed by the body can be synthesized from palmitate (C16:0) except the essential, polyunsaturated fatty acids such as linoleate and linolenate.
Griseofulvin
go.drugbank.com/drugs/DB00400ApprovedVet approvedAn antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Products: Fulvicin U/f Tab 250mg, Fulvicin Uf Tab 500mgEtomidate
go.drugbank.com/drugs/DB00292ApprovedInvestigationalImidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Categories: Hypnotics and SedativesProducts: ETOMIDATE-LIPURO 20MG/10ML INJ IN 10ML GA, ETOMIDE LIPURO 20MG/10ML IV ENJEKSIYONLUK EMULSIYON ICEREN AMPUL, 10 ADETPadimate O
go.drugbank.com/drugs/DB11570ApprovedPadimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA [L2153]. … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic effects on yeast i_n vivo_ [A32458].
Mixtures: Alba Botanica UN-petroleum Vanilla SPF18 Lip Balm, Alba Botanica UN-petroleum Cherry SPF18 Lip BalmCategories: Compounds used in a research, industrial, or household settingAsparaginase Escherichia coli
go.drugbank.com/drugs/DB00023ApprovedInvestigationalAsparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia … Therapeutic L-asparaginase from _E. coli_ works by depleting the levels of non-essential amino acid, asparagine, in lymphoblastic leukemic cells thus promoting apoptotic cell death [A31999].
Categories: Enzymes and Coenzymes, Antineoplastic and Immunomodulating AgentsSynonyms: Asparaginase IIZoledronic acid
go.drugbank.com/drugs/DB00399ApprovedInvestigational[A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. … [L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994.[A203120] Zoledronic acid was granted FDA approval on 20 August 2001.[L13712]
Categories: Drugs Affecting Bone Structure and Mineralization, zoledronic acid, calcium and colecalciferol, sequentialProducts: ACLASTA 5MG/100ML, ZOLE 1A PHARMA 5MG/100MLHuman Rho(D) immune globulin
go.drugbank.com/drugs/DB11597ApprovedIt was approved by FDA as treatment for suppression of rhesus (Rh) isoimmunization or chronic immune thrombocytopenic purpura (ITP) in adults. … Immune globullin was purified via ion-exchange chromatography method and prepared from pools of human plasma, where the donors are Rho (D)-negative donors who have been immunized with Rho(D)-positive RBCs
Mixtures: Winrho Sd Kit Inj, Winrho Sd Kit Inj.Categories: Amino Acids, Peptides, and Proteins, Immune Sera and Immunoglobulins