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Fovinaciclib

Fovinaciclib has a monoisotopic molecular weight of 548.3 Da. … Fovinaciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Fovinaciclib is a cyclin dependant kinase inhibitor.

Zeprumetostat

Zeprumetostat has a monoisotopic molecular weight of 548.34 Da. … Zeprumetostat is a small molecule drug. The usage of the INN stem '-metostat' in the name indicates that Zeprumetostat is a histone N-methyltransferase inhibitor.

Nizubaglustat

Nizubaglustat has a monoisotopic molecular weight of 433.23 Da. … Nizubaglustat is under investigation in clinical trial NCT07054515 (A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type

Proscillaridin

Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). … Studies suggest the potential cytotoxic and anticancer property of proscillaridin, based on evidence of the drug potently disrupting topoisomerase I and II activity at nanomolar drug concentrations [A27193

Dibromothymoquinone

At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem] … At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist.

Trefentanil

Trefentanil is not used in clinics due to the severity of its respiratory depression, though it is still used in research. … Trefentanil (A-3665) is a fentanyl analogue opioid developed in 1992. It is more potent and shorter acting than alfentanil.

NKG2D-ACE2 CAR-NK Cell

First used with autologous human T cells (CAR-T) as cancer immunotherapies, these receptors are now being engineered onto natural killer (NK) cells due to lower potential for graft-versus-host disease … These cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF.

R1295

R1295 is an integrin antagonist currently in clinical trials for the treatment of rheumatoid arthritis. … Integrins are associated to the pathology seen in some of the autoimmune diseases such as rheumatoid arthritis.

Olomorasib

Olomorasib has a monoisotopic molecular weight of 528.08 Da. … Olomorasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.

Pridinol