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Tauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawnTauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration. … [A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity.
Products: TAUROLITE 250 MG 100 KAPSULDelafloxacin
go.drugbank.com/drugs/DB11943ApprovedInvestigationalDelafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections, … It was approved in June 2017 under the trade name Baxdela for use in the treatment of acute bacterial skin and skin structure infections.
Categories: 4-Quinolones, Cytochrome P-450 CYP2C9 InducersProducts: Quofenix 450 mg Tablet, 10 ADET, Quofenix 300 mg İnfüzyonluk Çözelti Hazırlamada Kullanılacak Konsantre İçin Toz, 10 ADETDegarelix
go.drugbank.com/drugs/DB06699ApprovedInvestigationalChemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which are D-amino acids. FDA approved on December 24, 2008. … Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH.
Products: FIRMAGON ®80MG, FIRMAGON ® 120MGCopper gluconate
go.drugbank.com/drugs/DB11246ApprovedInvestigationalCopper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color. … According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005
Mixtures: Vitamin A C E W.niacinam.beta Car.and Min., Pregnancy Multivitamin Folic 5Products: Copper (gluconate) 2 Mg TabletsImidapril
go.drugbank.com/drugs/DB11783InvestigationalImidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Categories: Heterocyclic Compounds, 1-Ring, Agents Acting on the Renin-Angiotensin SystemProducts: TANATRIL TABLETS 5 mg, TANATRIL TABLETS 10 mgManganese cation
go.drugbank.com/drugs/DB06757ApprovedInvestigationalNutraceuticalManganese is a transition metal that was first described in the 19th and 20th centuries. … [A263687, A263662] In humans, manganese regulates several physiological processes by acting as a cofactor for proteins [A263657, A263662, A263667] making it an essential metal for normal development and
Synonyms: MANGANESE(2+), MANGANESE ION(2+)Mixtures: Calcium With Mg Zn Mn Cu CR Si and Vit. C & D, Coen.q10w.vit.c and E Beta-car.se Cu Zn MnEfalizumab
go.drugbank.com/drugs/DB00095ApprovedWithdrawnThe FDA approved efalizumab in 2003. It was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy (PML).[L43797] … Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin.
Products: RAPTIVA ®125 MG3-oxo-5-alpha-steroid 4-dehydrogenase 2
go.drugbank.com/bio_entities/BE0000585TargetEnzymeHumansCatalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed … Converts testosterone into 5-alpha-dihydrotestosterone (DHT), the most active androgen in the prostate, as it is the preferred ligand for androgen receptor (AR) transactivation, making this reaction a
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 2Synonyms: 5 alpha-SR2, Type II 5-alpha reductaseA disintegrin and metalloproteinase with thrombospondin motifs 5
go.drugbank.com/bio_entities/BE0003730TargetHumansMetalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chon...
Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 5Synonyms: ADAMTS-5, ADAM-TS 5Actin-related protein 2/3 complex subunit 5
go.drugbank.com/bio_entities/BE0004255TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in th...
Polypeptides: Actin-related protein 2/3 complex subunit 5