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Displaying results 6061 - 6070 of 10000 in total
  1. Indication

    Myasthenia Gravis

    go.drugbank.com/conditions/DBCOND0028961
    Drugs: Distigmine · Ephedrine · Neostigmine · Pyridostigmine · Zilucoplan
    Synonyms: MG - Myasthenia gravis
  2. Drug

    Sibutramine

    go.drugbank.com/drugs/DB01105
    ApprovedIllicitWithdrawn

    It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OBESTOP® 10 MG CAPSULAS, OBESTOPPOR 5 MG CAPSULAS
  3. Drug

    Phenylacetylglutamine

    go.drugbank.com/drugs/DB17167
    Experimental

    Synonyms: Antineoplaston as 2-1 component phenylacetylglutamine, L-glutamine, n2-(phenylacetyl)-
  4. Drug

    TRK-001

    go.drugbank.com/drugs/DB18577
    Investigational

    TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.

    Synonyms: Natural Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and Transforming Growth Factor-beta
  5. Drug

    C-(1-hydrogyl-beta-D-glucopyranosyl) formamide

    go.drugbank.com/drugs/DB02719
    Experimental

    Synonyms: (2R,3R,4S,5S,6R)-2,3,4,5-Tetrahydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-carboxamide, C-(1-hydrogyl-beta-D-glucopyranosyl) formamide
  6. Drug

    Paclitaxel docosahexaenoic acid

    go.drugbank.com/drugs/DB05297
    Investigational

    A combination of [docosahexaenoic Acid] (a natural fatty acid) and [paclitaxel] (an anticancer drug) being studied in the treatment of cancer. It is a type of mitotic inhibitor.

    Synonyms: Paclitaxel 2'-(all-cis-4,7,10,13,16,19-docosahexaenoate)
  7. Drug

    Vudalimab

    go.drugbank.com/drugs/DB18833
    Investigational

    Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate

    Synonyms: Immunoglobulin half-ig g1-kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)),, Pd-1 x ctla-4 dual checkpoint inhibitor xmab20717
  8. Drug

    Masoprocol

    go.drugbank.com/drugs/DB00179
    Investigational

    A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. … The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]

    Synonyms: meso-4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol, meso-β,γ-dimethyl-α,δ-bis(3,4-dihydroxyphenyl)butanCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Zidovudine

    go.drugbank.com/drugs/DB00495
    ApprovedInvestigational

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.

    Mixtures: N/A, LAVUZID® NCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  10. Drug

    Amphotericin B

    go.drugbank.com/drugs/DB00681
    ApprovedInvestigational

    Amphotericin B shows a high order of in vitro activity against many species of fungi. … ranging from 0.03 to 1.0 mcg/mL in vitro.

    Synonyms: AMPH-b, Amfotericina BSalts: Amphotericin B Cholesteryl Sulfate Complex