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Displaying results 6061 - 6070 of 10000 in total
  1. Drug

    Varespladib methyl

    go.drugbank.com/drugs/DB05737
    Investigational

    Studies showed that Varespladib methyl treatment resulted in significant positive changes on lipoproteins and inflammation.

  2. Drug

    VPM1002

    go.drugbank.com/drugs/DB15801
    Investigational

    BCG versions due to the lack of the RD2 genome segment. … The ability for mycobacterial antigens to reach the cytosol is due to this vaccine being engineered to secrete Hly which perforates phagosomal membranes.

  3. Drug

    Pamidronic acid

    go.drugbank.com/drugs/DB00282
    ApprovedInvestigational

    [A203111] Pamidronic acid was first described in the literature in 1977. … [A203111] Pamidronic acid was granted FDA approval on 31 October 1991.[L13835]

  4. Drug

    Nigericin

    go.drugbank.com/drugs/DB14056
    Experimental

    A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Vilazodone

    go.drugbank.com/drugs/DB06684
    ApprovedInvestigational

    Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].

  6. Drug

    Votucalis

    go.drugbank.com/drugs/DB05032
    Investigational

    rEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.

  7. Drug

    Plosaracetam

    go.drugbank.com/drugs/DB21594
    Investigational

    Plosaracetam has a monoisotopic molecular weight of 330.05 Da. … Plosaracetam is under investigation in clinical trial NCT05199142 (A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive

  8. Drug

    Istisociclib

    go.drugbank.com/drugs/DB21703
    Investigational

    Istisociclib has a monoisotopic molecular weight of 287.21 Da. … Istisociclib is under investigation in clinical trial NCT04718675 (A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer

  9. Drug

    Atirmociclib

    go.drugbank.com/drugs/DB21733
    Investigational

    Atirmociclib has a monoisotopic molecular weight of 463.18 Da. … Atirmociclib is under investigation in clinical trial NCT06760637 (Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment

  10. Drug

    Piclidenoson

    go.drugbank.com/drugs/DB05511
    Investigational

    CF101 is supplied as an oral drug and has an excellent safety profile. … CF 101 (known generically as IB-MECA) is an anti-inflammatory drug for rheumatoid arthritis patients. Its novel mechanism of action relies on antagonism of adenoside A3 receptors.