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Formoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigationalFormoterol is an inhaled beta<sub>2</sub>-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. … [L11256] It is available as a single-entity product [L10986,L11223] and in several formulations in combination with both inhaled corticosteroids [L10995,L10619] and long-acting muscarinic antagonists.
Mixtures: FOSTER NEXTHALER 100UG/6UG, FOSTER NEXTHALER 100UG/6UGSynonyms: N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamideProtriptyline
go.drugbank.com/drugs/DB00344ApprovedThey contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.
Synonyms: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, N-methyl-5H-dibenzo[a,d]cycloheptene-5-propanamineProducts: Triptil Tab 10mgTobramycin
go.drugbank.com/drugs/DB00684ApprovedInvestigational[L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics … [A232294] Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics
Mixtures: TOBRAMICINA E DESAMETASONE EG, TOBRAMICINA E DESAMETASONE DOC GENERICIProducts: Nebcin Inj 10mg/ml, Nebcin Inj 10mg/ml (vantage Vial)Panobinostat
go.drugbank.com/drugs/DB06603ApprovedInvestigationalPanobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. … The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted
Synonyms: (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide, 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)-Products: FARYDAK HARD GELATIN CAPSULE 10mgClomipramine
go.drugbank.com/drugs/DB01242ApprovedInvestigationalVet approvedThey contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.
Synonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamineProducts: Gen-clomipramine - Tab 10mg, ANAFRANIL 10MGIdarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Products: Idamycin - Cap 10mg, Idamycin Pws 10mg/vialEmpagliflozin
go.drugbank.com/drugs/DB09038ApprovedInvestigationalin 2014. … Empagliflozin was further approved by the EMA in March 2022 and Health Canada in April 2022, making it the first and only approved treatment in Europe and Canada for adults with symptomatic chronic heart
Mixtures: Glyxambi Film-Coated Tablets 10mg/5mg, Jardiance Duo 12.5mg/ 1000mg Film-coated tabletsCategories: Drugs Used in DiabetesChlorpheniramine
go.drugbank.com/drugs/DB01114ApprovedInvestigationalA histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications.
Synonyms: 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine, 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamineMixtures: COUGH - EN, COUGH - EN PLUSGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigational[L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999. … Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques.
Products: NOVOLEX 0.25 MG/0.5 ML SOLUCIÓN INYECTABLE EN JERINGA PRECARGADA, Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer FertigspritzePentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnIt is formed by reacting pentaerythritol (C5H12O4), an alcohol commonly used in paints and varnishes, with nitric acid (HNO2). The reacting solution is chilled to precipitate the PETN. … Interestingly, this drug was studied for potential benefits in chronic ischemic heart failure patients.
Categories: Vasodilators Used in Cardiac DiseasesSynonyms: TEN