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Displaying results 6121 - 6130 of 10000 in total
  1. Drug

    Vorinostat

    go.drugbank.com/drugs/DB02546
    ApprovedInvestigational

    It is the first in a new class of agents known as histone deacetylase inhibitors. … A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4 - 4.4 months in earlier

    Products: ZOLINZA®VORINOSTAT 100 MG CAPSULAS
  2. Drug

    Sus scrofa skin

    go.drugbank.com/drugs/DB10606
    Approved

    Sus scrofa skin or pelt is used in allergenic testing.

    Products: PiGe ll Real Skin Eye, PiGe ll Real Skin Neck Pack
  3. Target

    Transcobalamin-1

    go.drugbank.com/bio_entities/BE0000238
    TargetTransporterCarrierHumans

    Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach

    Polypeptides: Transcobalamin-1Synonyms: TC-1
  4. Target

    Arginase-1

    go.drugbank.com/bio_entities/BE0000286
    TargetEnzymeHumans

    Catalyzes the final step of the urea cycle by hydrolyzing L-arginine into urea, a nitrogenous waste product, and L-ornithine, a precursor to proline and polyamines; the urea cycle occurs primarily in the liver and, to a lesser extent, in...

    Polypeptides: Arginase-1
  5. Target

    Sialidase-1

    go.drugbank.com/bio_entities/BE0000914
    TargetHumans

    Lysosomal exo-alpha-sialidase that catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex (PubMed:1469...

    Polypeptides: Sialidase-1Synonyms: Neuraminidase-1, N-acetyl-alpha-neuraminidase 1
  6. Target

    Lipase 1

    go.drugbank.com/bio_entities/BE0001696
    TargetYeast

    Polypeptides: Lipase 1
  7. Target

    Flavodoxin 1

    go.drugbank.com/bio_entities/BE0003038
    TargetEscherichia coli (strain K12)

    Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase.

    Polypeptides: Flavodoxin 1Synonyms: Flavodoxin-1
  8. Target

    Endothelin-1

    go.drugbank.com/bio_entities/BE0003384
    TargetHumans

    Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G protein-coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial ...

    Polypeptides: Endothelin-1Synonyms: Preproendothelin-1
  9. Target

    Protease 1

    go.drugbank.com/bio_entities/BE0004345
    TargetAchromobacter lyticus

    Polypeptides: Protease 1
  10. Target

    Epsin-1

    go.drugbank.com/bio_entities/BE0004452
    TargetHumans

    Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis (Pu...

    Polypeptides: Epsin-1Synonyms: EPS-15-interacting protein 1