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Displaying results 6131 - 6140 of 10000 in total
  1. Drug

    Isavuconazole

    go.drugbank.com/drugs/DB11633
    ApprovedInvestigational

    It is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026]. … Isavuconazole is an triazole antifungal with broad spectrum of activity and good safety profile [A32026].

  2. Drug

    Norfloxacin succinil

    go.drugbank.com/drugs/DB20858
    Experimental

    The usage of the INN stem '-oxacin' in the name indicates that Norfloxacin succinil is a nalidixic acid derivative antibacterial. Norfloxacin succinil has a monoisotopic molecular weight of 419.15 Da. … The usage of the INN stem '-nil' in the name indicates that Norfloxacin succinil is a benzodiazepine receptor antagonist/agonist.

  3. Drug

    Tunodafil

    go.drugbank.com/drugs/DB21576
    Investigational

    Tunodafil is under investigation in clinical trial NCT05976503 (A Study of the Interaction of Tunodafil Hydrochloride Tablets and Alcohol). Tunodafil has a monoisotopic molecular weight of 487.23 Da. … The usage of the INN stem '-afil' in the name indicates that Tunodafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action.

  4. Drug

    Tamuzimod

    go.drugbank.com/drugs/DB21621
    Investigational

    Tamuzimod has a monoisotopic molecular weight of 545.0 Da. … The usage of the INN stem '-imod' in the name indicates that Tamuzimod is a immunomodulator, both stimulant/suppressive and stimulant.

  5. Drug

    Pracinostat

    go.drugbank.com/drugs/DB05223
    Investigational

    Pracinostat is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in clinical trials, allowing oral dosing. … Data demonstrate that Pracinostat is a potent and effective anti-tumor drug with potential as an oral therapy for a variety of human hematological and solid tumors.

  6. Drug

    Enbucrilate

    go.drugbank.com/drugs/DB12358
    Investigational

    Enbucrilate is under investigation in clinical trial NCT02468206 (Secondary Prophylaxis of Gastric Variceal Bleed).

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N-butyl cyanoacrylate, N-butyl-2-cyanoacrylate
  7. Drug

    Coagulation factor VIIa Recombinant Human

    go.drugbank.com/drugs/DB00036
    ApprovedInvestigational

    Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.

  8. Drug

    Astodrimer

    go.drugbank.com/drugs/DB11854
    Investigational

    Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Rotenone

    go.drugbank.com/drugs/DB11457
    ExperimentalVet approved

    Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Solriamfetol

    go.drugbank.com/drugs/DB14754
    ApprovedInvestigational

    Solriamfetol was given FDA approval in 2019[FDA Label]. … Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated