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Displaying results 6131 - 6140 of 10000 in total
  1. Drug

    Trypsin

    go.drugbank.com/drugs/DB11237
    ApprovedInvestigationalVet approved

    Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. … Trypsin contains a nucleophilic residue Ser in the enzyme active site which attacks the carbonyl moiety of the substrate peptide bond to form an acyl-enzyme intermediate [A27241].

  2. Drug

    Alofanib

    go.drugbank.com/drugs/DB20918
    Investigational

    Alofanib is under investigation in clinical trial NCT04071184 (Study of Alofanib in Patients With Metastatic Gastric Cancer). Alofanib has a monoisotopic molecular weight of 413.07 Da. … Alofanib is a small molecule drug. The usage of the INN stem '-anib' in the name indicates that Alofanib is a angiogenesis inhibitor.

  3. Drug

    MEM 1003

    go.drugbank.com/drugs/DB05547
    Investigational

    MEM 10003 was under investigation in clinical trial NCT00257673 (Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease) for the treatment of Alzheimer's Disease

    Synonyms: VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C, CALCIUM CHANNEL, L TYPE, ALPHA-1 POLYPEPTIDE, ISOFORM 1, CARDIAC MUSCLE
  4. Drug

    INCB-9471

    go.drugbank.com/drugs/DB12960
    Investigational

    INCB-9471 is a novel, orally available CCR5 antagonist that is part of a new class of drugs to treat HIV/AIDS. It is a potent, selective inhibitor of the HIV-1 virus.

  5. Drug

    Dichloroacetic acid

    go.drugbank.com/drugs/DB08809
    ApprovedInvestigationalWithdrawn

    DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization and removal of a wide variety of skin and tissue lesions), but was cancelled post market … A phase 1 study in 5 patients concluded that DCA was safe, but wasn't designed to establish effectiveness.

  6. Drug

    ARC183

    go.drugbank.com/drugs/DB05124
    Experimental

    ARC183 is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity … The key advantage of ARC183 compared to other thrombin inhibitors is its rapid onset of action and short half-life, giving it the potential to be an ideal agent for medical procedures that require rapid

  7. Drug

    IRX-5183

    go.drugbank.com/drugs/DB05653
    Investigational

  8. Drug

    Vibriolysin

    go.drugbank.com/drugs/DB05135
    Experimental

    It is a new agent for enzymatic debridement, shown to rapidly and thoroughly hydrolyze burn wound eschar within full-thickness wounds. … Vibriolysin is a proteolytic enzyme secreted by the marine microorganism Vibrio proteolyticus.

  9. Drug

    ADC4022

    go.drugbank.com/drugs/DB05195
    Investigational

    ADC4022 is an investigational medicine for the treatment of Chronic Obstructive Pulmonary Disease (COPD) and severe asthma.

  10. Drug

    Safimaltib

    go.drugbank.com/drugs/DB21528
    Investigational

    Safimaltib has a monoisotopic molecular weight of 467.08 Da. … Safimaltib is a small molecule drug. Safimaltib is under investigation in clinical trial NCT06788509 (A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring).