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Alfaxalone
go.drugbank.com/drugs/DB11371ExperimentalVet approvedIt is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. … Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin.
Posizolid
go.drugbank.com/drugs/DB04850InvestigationalIn July 2002, after completion of phase I trials in December 2001, AstraZeneca announced that they were no longer pursuing the development of Posizolid, presumably due to negative trial results (though … Posizolid (AZD2563) is an oxazolidinone antibiotic.
Sarafloxacin
go.drugbank.com/drugs/DB11491ApprovedVet approvedWithdrawnSarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Cefodizime
go.drugbank.com/drugs/DB13470InvestigationalCefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity.[A275053, A275058]
ILS-920
go.drugbank.com/drugs/DB15422InvestigationalILS-920 is under investigation in clinical trial NCT00827190 (Study Evaluating Single Ascending Doses Of ILS-920).
Valerian
go.drugbank.com/drugs/DB13196ApprovedValerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. … [DB00313] is a derivative of valeric acid, which is obtained from the plant root.
Products: Valerian Tct 435mg/mlBudigalimab
go.drugbank.com/drugs/DB16668InvestigationalBudigalimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination … With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
Mequitazine
go.drugbank.com/drugs/DB01071InvestigationalMequitazine is a histamine H1 antagonist (antihistamine). … It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.
MORAb-066
go.drugbank.com/drugs/DB17347InvestigationalMORAb-066 is a humanized antibody directed against tissue factor (TF). It is being investigated in pancreatic cancer.
Gevokizumab
go.drugbank.com/drugs/DB12119InvestigationalGevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.