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Dyclonine
go.drugbank.com/drugs/DB00645ApprovedInvestigationalDyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Synonyms: 4-n-butoxy-β-(1-piperidyl)propiophenone, 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanoneProducts: Sucrets MS Wintergreen, Sucrets Extra Strength Mint Flav.loz 3mgApraclonidine
go.drugbank.com/drugs/DB00964ApprovedInvestigationalApraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Synonyms: 4-AminoclonidineCategories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AgonistsImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigationalBrian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". … [A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidideMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigational[L7180] Methotrexate was granted FDA approval on 7 December 1953.[L7198] … Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis.
Synonyms: 4-amino-N(10)-methylpteroylglutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acidCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexAcoramidis
go.drugbank.com/drugs/DB17999ApprovedInvestigationalAcoramidis is a small molecule stabilizer of transthyretin (TTR) for use in patients with TTR amyloidosis. … [A264768] Although they share a mechanism of action, acoramidis is more selective for TTR and is a more potent stabilizer when compared to tafamidis.
Synonyms: 3-(3-(3,5-dimethyl-1h-pyrazol-4-yl)propoxy)-4-fluorobenzoic acidCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2C9 InhibitorsAcetaminophen
go.drugbank.com/drugs/DB00316ApprovedInvestigationalpregnancy remains a first-line therapeutic option when used at the lowest effective dose for the shortest required duration. … FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent tablets, injection, suppository, and other forms.
Synonyms: N-acetyl-p-aminophenol, 4-acetamidophenolInternational brands: Dapa X-S, Anacin-3Sufentanil
go.drugbank.com/drugs/DB00708ApprovedInvestigationalSufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. … (AcelRx), was approved on November 2, 2018 [L4717].
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide, N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE
go.drugbank.com/drugs/DB07829ExperimentalSynonyms: 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE
go.drugbank.com/drugs/DB08522ExperimentalSynonyms: 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLEOxybuprocaine
go.drugbank.com/drugs/DB00892ApprovedInvestigationalOxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology.
Synonyms: 4-Amino-3-n-butoxy-benzoesäure-diäthylaminoäthylester, 4-Amino-3-butoxy-2-(diethylamino)ethyl ester benzoic acidMixtures: AMIGDAL-B®, BUCALIV® TABLETA MASTICABLE