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Displaying results 6271 - 6280 of 10000 in total
  1. Target

    Potassium voltage-gated channel subfamily KQT member 4

    go.drugbank.com/bio_entities/BE0002399
    TargetHumans

    KCNQ4/Kv7.4 channel is composed of 4 pore-forming subunits assembled as tetramers (PubMed:34767770).

    Polypeptides: Potassium voltage-gated channel subfamily KQT member 4Synonyms: KQT-like 4
  2. Target

    UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimerase

    go.drugbank.com/bio_entities/BE0002630
    TargetPseudomonas aeruginosa

    Polypeptides: UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimeraseSynonyms: UDP-GlcNAcA 4-epimerase
  3. Target

    Potassium voltage-gated channel subfamily A member 4

    go.drugbank.com/bio_entities/BE0004502
    TargetHumans

    Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. Th...

    Polypeptides: Potassium voltage-gated channel subfamily A member 4
  4. Target

    A disintegrin and metalloproteinase with thrombospondin motifs 4

    go.drugbank.com/bio_entities/BE0004687
    EnzymeTargetHumans

    Cleaves aggrecan, a cartilage proteoglycan, at the '392-Glu-|-Ala-393' site and may be involved in its turnover (PubMed:10356395, PubMed:10827174). Also cleaves COMP (PubMed:39672391). May play an important role in the destruction of agg...

    Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 4Synonyms: ADAMTS-4, ADAM-TS 4
  5. Target

    C-type lectin domain family 4 member E

    go.drugbank.com/bio_entities/BE0009096
    TargetHumans

    Calcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: recognizes damage-associated molecular patterns (DAMPs) of abnormal self and pathogen-associated molecular patterns (PAMPs) of bacter...

    Polypeptides: C-type lectin domain family 4 member E
  6. Target

    C-type lectin domain family 4 member C

    go.drugbank.com/bio_entities/BE0010522
    TargetHumans

    Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed:21880719, PubMed:25995448).

    Polypeptides: C-type lectin domain family 4 member C
  7. Drug

    Semaglutide

    go.drugbank.com/drugs/DB13928
    ApprovedInvestigational

    Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity. … [L8678] The subcutaneous injection is administered once weekly and the tablet is administered once a day.

    Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsProducts: Wegovy® 1 mg/0.5 mL (1 mg/dose) Solution for injection in pre-filled pen, Ozempic® 1.34 mg/ml (1 mg/dose) Solution for injection in pre-filled pen
  8. Indication

    Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 4

    go.drugbank.com/conditions/DBCOND0093777
    Drugs: Voxilaprevir
    Synonyms: Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 4
  9. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … It was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug [L2002].

    Synonyms: 5'-NoranhydrovinblastineCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 Substrates
  10. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. … zinc as a marker of these diseases [L2097].

    Mixtures: Calcium With Mg Zn Mn Cu CR Si and Vit. C & D, FENYSOL-Z 40 MG + 15 MG/5 ML ŞURUP, 100 MLProducts: ZINCLOMIN 15 MG/5 ML 100 ML SURUP, ZINCO-K 15MG/5 ML 28 KASIK SURUP