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Displaying results 621 - 630 of 10000 in total
  1. Drug

    Synthetic Conjugated Estrogens, A

    go.drugbank.com/drugs/DB09317
    Approved

    However, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control … Pharmacologic estrogen products are available in a variety of formats.

  2. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    [A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults. … [A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with [phentermine] for chronic weight management therapy in adults.

    Products: TOPIRAMATO EG, Topamax 15 mg Granulat in Kapseln
  3. Indication

    Amenorrhea, Postpartum

    go.drugbank.com/conditions/DBCOND0110846
    Drugs: Medroxyprogesterone acetate · Metergoline · Progesterone
  4. Drug

    Racementhol

    go.drugbank.com/drugs/DB14123
    ApprovedInvestigational

    Mixtures: Lidothol ES, Lidothol ESProducts: Nosk EX Sleep, Ez Massager 2 Original
  5. Drug

    Belinostat

    go.drugbank.com/drugs/DB05015
    ApprovedInvestigational

    The safety and efficacy of belinostat is currently being evaluated for use in combination with traditional front-line therapies for the treatment of PTCL. … It was developed as an orphan drug to target hematological malignancies and solid tumors by TopoTarget.

    Synonyms: (2E)-N-HYDROXY-3-(3-(PHENYLSULFAMOYL)PHENYL)PROP-2-ENAMIDE, N-Hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
  6. Drug

    Ambroxol

    go.drugbank.com/drugs/DB06742
    ApprovedInvestigational

    Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents. … role in the body’s natural defence mechanisms.

    Mixtures: LARITOL EX, TUKOL EXSynonyms: Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)-, N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol
  7. Drug

    Lindane

    go.drugbank.com/drugs/DB00431
    ApprovedWithdrawn

    In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical … treatment of pediculosis capitis (head lice), pediculosis pubis (pubic lice), or scabies in patients greater than two years of age who cannot tolerate or have failed first-line treatment.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Tilmicosin

    go.drugbank.com/drugs/DB11471
    InvestigationalVet approved

    It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with _Mannheimia haemolytica_.

    Products: EM-MICOFEED 10% Granules
  9. Drug

    Deferasirox

    go.drugbank.com/drugs/DB01609
    ApprovedInvestigational

    Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.

    Categories: Compounds used in a research, industrial, or household settingProducts: DEFERASIROX EG
  10. Drug

    Imatinib

    go.drugbank.com/drugs/DB00619
    ApprovedInvestigational

    Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". … [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA; however, its European approval has been withdrawn in October 2023.[A263036,L49746,L49751]

    Products: IMATINIB EG