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Ibuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39075] Ibuprofen was finally patented in 1961 and this drug was first launched against rheumatoid arthritis in the UK in 1969 and USA in 1974. It was the first available over-the-counter NSAID. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.
Mixtures: NUROFEN INFLUENZA E RAFFREDDORE, NUROFEN INFLUENZA E RAFFREDDOREProducts: IBUPROFEN 400MG IPA/DR SAN, IBUPROFENE EGGlucosamine
go.drugbank.com/drugs/DB01296ApprovedOsteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional b...
Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: GLUCOSAMINA SOLFATO EG, GLUCOSAMINA E-PHARMA TRENTOCelecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigational[A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. … [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998.
Products: CELECOXIB EGAluminum zirconium octachlorohydrex gly
go.drugbank.com/drugs/DB11200ApprovedCurrently, the FDA allows the inclusion of this substance in concentrations of up to 20% in antiperspirants [L2012]. … Interestingly, this chemical has been studied in relation to its possible impact on the microbiome of the human underarms [A32967].
Mixtures: Lactovit DEODORANT ROLL-ON MEN INVISIBLEProducts: Dior Homme Sans Alcohol Free Antiperspirant, DURADRY AM End GameLacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigational[A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008. … [A262681] It was granted approval by Health Canada in September 2010.[L49206]
Synonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDEProducts: LACOSAMIDE EG, LASOMID INTadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigational[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.
Categories: Drugs Used in Erectile Dysfunction, Drugs Used in Benign Prostatic HypertrophyProducts: TADALAFIL EG, TADALAFIL EG STADAAcyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigational[L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. … [L7321] Acyclovir was granted FDA approval on 29 March 1982.[L7318]
Products: ACICLOVIR EGMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system.
Synonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideProducts: METOPRAX 10 MG/2 ML IM/IV ENJ. COZ. ICEREN AMPUL, 5 ADETPixantrone
go.drugbank.com/drugs/DB06193ApprovedWithdrawnPixantrone dimaleate, administered intravenously, was designed by Cell Therapeutics Incorporated as an alternative second line therapy in refractory or relapsed NHL. … Pixantrone was designed to treat relapsed or refractory aggressive non-Hodgkin's lymphoma(NHL) in patients who have failed two prior lines of therapy. [2] For patients suffering from NHL, first line therapies
Bortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigational[L14180] However, multiple mechanisms may be involved in the anticancer activity of bortezomib.[A204083] Bortezomib was first synthesized in 1995. … [A204083] In May 2003, bortezomib became the first anticancer proteasome inhibitor that was approved by the FDA under the trade name VELCADE.
Synonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideProducts: BORTEZOMIB EG