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Methotrimeprazine
go.drugbank.com/drugs/DB01403Approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p604) … It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine.
Synonyms: (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine, (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazineCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsAtracurium besylate
go.drugbank.com/drugs/DB00732ApprovedIts lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents
Categories: Heterocyclic Compounds, 2-RingProducts: DEMATRAC 50 MG/5 ML İNFÜZYON İÇİN SOLÜSYON İÇEREN AMPUL, 10 AMPUL, Notrixum Injection 10 mg/mlMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Categories: Heterocyclic Compounds, 2-RingSynonyms: (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl esterCefazolin
go.drugbank.com/drugs/DB01327ApprovedInvestigationalIt attains high serum levels and is excreted quickly via the urine.
Mixtures: CEFAMEZIN 500 MG IM ENJEKTABL TOZ İÇEREN FLAKON, 1 ADET, CEFAMEZIN 1000 MG IM STERİL ENJEKTABL TOZ İÇEREN FLAKON, 1 ADETCategories: Heterocyclic Compounds, 2-RingFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalOnce bound to heparin or HS, the anticoagulant activity of ATIII is potentiated by 1000-fold. Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold. … angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI); and in the management of ST segment elevation myocardial infarction (STEMI).
Products: ARIXTRA 10 MG/0.8 ML S.C. ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 2 ADET, ARIXTRA 5MG/0.4 ML S.S. ENJ. COZELTI ICEREN KULLANIMA HAZIR SIRINGA, 10 ADETCaffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigational[L9863] According to an article from 2017, more than 15 million babies are born prematurely worldwide. This correlates to about 1 in 10 births. … [A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, which are different than coffee beans.
Mixtures: ALJIL 150 MG/300 MG/50 MG TABLET, 20 ADET, DERMAN 300 MG/100 MG/50 MG KAŞE, 1 KAŞECategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSuccinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigational[A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. … Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and lasting between four to six minutes, make succinylcholine particularly useful in the setting of short
Synonyms: 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)Products: QUELICIN 1000 MG/10 ML, ETHICHOLINE INJECTION 100 mg/2 mlAbrocitinib
go.drugbank.com/drugs/DB14973ApprovedInvestigational[A244549] Abrocitinib was approved by the European Commission on December 10, 2021, for the treatment of moderate-to-severe atopic dermatitis (AD) in adults who are candidates for systemic therapy. … [L39784] On January 14, 2022, the FDA approved abrocitinib for the treatment of refractory, moderate-to-severe AD in adults whose disease is not adequately controlled with other systemic drug products,
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: CİBİNQO 100 MG FİLM KAPLI TABLET, 28 ADET, CİBİNQO 50 MG FİLM KAPLI TABLET, 28 ADETEplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalregulatory feedback of aldosterone on renin secretion. … Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: EPLEDAY 50 MG FILM KAPLI TABLET, 100 ADET, EPLEDAY 25 MG FILM KAPLI TABLET, 100 ADETCelecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigational[A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. … [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998.
Categories: tramadol and celecoxib, Cyclooxygenase-2 (COX-2) InhibitorsSynonyms: p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide