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Calpain-2 catalytic subunit
go.drugbank.com/bio_entities/BE0012693TargetHumansCalcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cl...
Polypeptides: Calpain-2 catalytic subunitSynonyms: CANP 2, Calpain-2 large subunitOX-2 membrane glycoprotein
go.drugbank.com/bio_entities/BE0013092TargetHumansCostimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues
Polypeptides: OX-2 membrane glycoproteinOligodendrocyte transcription factor 2
go.drugbank.com/bio_entities/BE0014194TargetHumansAntagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development
Polypeptides: Oligodendrocyte transcription factor 2Synonyms: Protein kinase C-binding protein 2Sigma intracellular receptor 2
go.drugbank.com/bio_entities/BE0015084TargetHumansSigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking
Polypeptides: Sigma intracellular receptor 2Synonyms: Sigma-2 receptorSodium/hydrogen exchanger 2
go.drugbank.com/bio_entities/BE0020524TransporterHumansPlasma membrane Na(+)/H(+) antiporter. Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) (PubMed:10444453). Major apical Na(+)/H(+) exchanger in the base of the colonic crypt. Controls in the colonic...
Polypeptides: Sodium/hydrogen exchanger 2Synonyms: NHE-2, Na(+)/H(+) exchanger 2Ferric derisomaltose
go.drugbank.com/drugs/DB15617ApprovedInvestigational[A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. This drug is a complex of iron (III) hydroxide and derisomaltose. … Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells.
Products: MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/ML, Diafer 50 mg/ml InjektionslösungCysteinyl leukotriene receptor 2
go.drugbank.com/bio_entities/BE0000099TargetHumansReceptor for cysteinyl leukotrienes. The response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary ...
Polypeptides: Cysteinyl leukotriene receptor 2SEC14-like protein 2
go.drugbank.com/bio_entities/BE0000256TargetTransporterCarrierHumansCarrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrieno...
Polypeptides: SEC14-like protein 2Mitochondrial ornithine transporter 2
go.drugbank.com/bio_entities/BE0000258TargetHumansMitochondrial transporter of the positively charged amino acids ornithine, lysine and arginine, and the neutral amino acid citrulline (PubMed:12807890). In addition, transports the basic amino acids histidine, homoarginine, and asymmetri...
Polypeptides: Mitochondrial ornithine transporter 2Synonyms: Solute carrier family 25 member 2Interferon gamma receptor 2
go.drugbank.com/bio_entities/BE0000467TargetHumansAssociates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:7673114, PubMed:8124716). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:15356148, PubMed:7673114,...
Polypeptides: Interferon gamma receptor 2Synonyms: IFN-gamma receptor 2