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Displaying results 6321 - 6330 of 10000 in total
  1. Target

    Inactive dihydropteroate synthase 2

    go.drugbank.com/bio_entities/BE0002087
    TargetMycobacterium leprae (strain TN)

    Has very low affinity for the DHPS substrate 6-hydroxymethyl-7,8-dihydropterin-pyrophosphate, but can bind the inhibitor dapsone. Seems to lack dihydropteroate synthase activity, and does probably not function in folate metabolism (By si...

    Polypeptides: Inactive dihydropteroate synthase 2Synonyms: DHPS 2, Dihydropteroate pyrophosphorylase 2
  2. Target

    Prolyl 3-hydroxylase 2

    go.drugbank.com/bio_entities/BE0002206
    TargetEnzymeHumans

    Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens (PubMed:18487197). Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens ...

    Polypeptides: Prolyl 3-hydroxylase 2
  3. Target

    Adenylosuccinate synthetase isozyme 2

    go.drugbank.com/bio_entities/BE0002228
    TargetHumans

    Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP

    Polypeptides: Adenylosuccinate synthetase isozyme 2Synonyms: AdSS 2, AMPSase 2
  4. Target

    Mitochondrial glutamate carrier 2

    go.drugbank.com/bio_entities/BE0002275
    TransporterHumans

    Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system)

    Polypeptides: Mitochondrial glutamate carrier 2Synonyms: GC-2, Glutamate/H(+) symporter 2
  5. Target

    Putative pteridine reductase 2

    go.drugbank.com/bio_entities/BE0002691
    TargetTrypanosoma cruzi

    Polypeptides: Putative pteridine reductase 2
  6. Target

    2-keto-3-deoxygluconokinase

    go.drugbank.com/bio_entities/BE0003107
    TargetThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)

    Polypeptides: 2-keto-3-deoxygluconokinaseSynonyms: 2-keto-3-deoxy-gluconate kinase, 3-deoxy-2-oxo-D-gluconate kinase
  7. Target

    Leukotriene B4 receptor 2

    go.drugbank.com/bio_entities/BE0003489
    TargetHumans

    Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank ...

    Polypeptides: Leukotriene B4 receptor 2Synonyms: LTB4-R 2
  8. Target

    Copper-transporting ATPase 2

    go.drugbank.com/bio_entities/BE0003664
    TransporterHumans

    Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload

    Polypeptides: Copper-transporting ATPase 2Synonyms: Copper pump 2
  9. Target

    Penicillin-binding protein 2

    go.drugbank.com/bio_entities/BE0003688
    TargetBacteroides fragilis

    Polypeptides: Penicillin-binding protein 2
  10. Target

    Adenylate cyclase type 2

    go.drugbank.com/bio_entities/BE0003732
    TargetHumans

    Catalyzes the formation of the signaling molecule cAMP in response to G protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in si...

    Polypeptides: Adenylate cyclase type 2Synonyms: Adenylyl cyclase 2, ATP pyrophosphate-lyase 2