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Displaying results 6351 - 6360 of 10000 in total
  1. Target

    Penicillin-binding protein 2

    go.drugbank.com/bio_entities/BE0008389
    TargetStaphylococcus aureus

    Polypeptides: Penicillin-binding protein 2
  2. Target

    Diacylglycerol O-acyltransferase 2

    go.drugbank.com/bio_entities/BE0008719
    EnzymeTargetHumans

    Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides (PubMe...

    Polypeptides: Diacylglycerol O-acyltransferase 2Synonyms: Diglyceride acyltransferase 2
  3. Target

    Alpha-2-HS-glycoprotein

    go.drugbank.com/bio_entities/BE0009048
    TargetHumans

    Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions

    Polypeptides: Alpha-2-HS-glycoproteinSynonyms: Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein
  4. Target

    LIM domain kinase 2

    go.drugbank.com/bio_entities/BE0009456
    TargetHumans

    Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, Pub...

    Polypeptides: LIM domain kinase 2Synonyms: LIMK-2
  5. Target

    Transmembrane protease serine 2

    go.drugbank.com/bio_entities/BE0009920
    TargetHumans

    Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption

    Polypeptides: Transmembrane protease serine 2
  6. Target

    Serum paraoxonase/arylesterase 2

    go.drugbank.com/bio_entities/BE0009921
    TargetHumans

    Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, a...

    Polypeptides: Serum paraoxonase/arylesterase 2Synonyms: PON 2, A-esterase 2
  7. Target

    Cancer/testis antigen 2

    go.drugbank.com/bio_entities/BE0010686
    TargetHumans

    Polypeptides: Cancer/testis antigen 2Synonyms: Autoimmunogenic cancer/testis antigen NY-ESO-2
  8. Target

    Proteinase-activated receptor 2

    go.drugbank.com/bio_entities/BE0010726
    TargetHumans

    Associates with a subset of G proteins alpha subunits such as GNAQ, GNA11, GNA14, GNA12 and GNA13, but probably not with G(o)-alpha, G(i) subunit alpha-1 and G(i) subunit alpha-2.

    Polypeptides: Proteinase-activated receptor 2Synonyms: PAR-2
  9. Target

    Apoptosis regulator Bcl-2

    go.drugbank.com/bio_entities/BE0010919
    TargetRat

    Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system...

    Polypeptides: Apoptosis regulator Bcl-2Synonyms: Bcl-2
  10. Target

    CCN family member 2

    go.drugbank.com/bio_entities/BE0013178
    TargetHumans

    Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenes...

    Polypeptides: CCN family member 2Synonyms: Cellular communication network factor 2