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Displaying results 631 - 640 of 10000 in total
  1. Drug

    Rosiglitazone

    go.drugbank.com/drugs/DB00412
    ApprovedInvestigational

    Recent research has suggested that rosiglitazone may also be of benefit to a subset of patients with Alzheimer's disease not expressing the ApoE4 allele. … This is the subject of a clinical trial currently underway.

    Categories: Peroxisome Proliferator Receptor gamma Agonist, Peroxisome Proliferator-activated Receptor ActivityInternational brands: Sheng Ao
  2. Target

    Leucine-rich repeat-containing G protein-coupled receptor 5

    go.drugbank.com/bio_entities/BE0010835
    TargetHumans

    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle.

    Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5Synonyms: G protein-coupled receptor 49, G protein-coupled receptor 67
  3. Drug

    Pectin

    go.drugbank.com/drugs/DB11158
    ApprovedInvestigationalVet approved

    Under the FDA regulation, pectin qualifies as a GRAS (generally recognized as safe) food substance. This status allows pectin to be used with no limitations.[L1960] … [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or as acid amides.

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Bretylium

    go.drugbank.com/drugs/DB01158
    Approved

    Recent evidence has shown that bretylium may also inhibit the Na,K-ATPase by binding to the extracellular K-site.

  5. Drug

    Capsaicin

    go.drugbank.com/drugs/DB06774
    ApprovedInvestigational

    The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia. … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: Antiphlogistine Rub A-535 Capsaicin Gel, Antiphlogistine Rub A-535 Capsaicin Liquid
  6. Indication

    Deficiency of the interleukin-1 receptor antagonist

    go.drugbank.com/conditions/DBCOND0008480
    Drugs: Anakinra · Rilonacept
    Synonyms: Deficiency of interleukin-1 receptor antagonist, Interleukin-1 receptor antagonist deficiency
  7. Drug

    Vernakalant

    go.drugbank.com/drugs/DB06217
    ApprovedInvestigational

    Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. … It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates.

  8. Drug

    Tilmicosin

    go.drugbank.com/drugs/DB11471
    InvestigationalVet approved

    Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with _Mannheimia haemolytica_.

    Products: Pulmotil AC, Aqueous Concentrate, 250mg/ml
  9. Indication

    Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer

    go.drugbank.com/conditions/DBCOND0111347
    Drugs: Vepdegestrant
    Synonyms: Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer
  10. Drug

    Calcium citrate

    go.drugbank.com/drugs/DB11093
    ApprovedInvestigational

    Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.

    Mixtures: Eden With Calcium and Vitamin DCategories: Compounds used in a research, industrial, or household setting