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Displaying results 631 - 640 of 4822 in total
  1. Drug

    Asciminib

    go.drugbank.com/drugs/DB12597
    ApprovedInvestigational

    [A241065] Asciminib is unique in that it acts as an allosteric inhibitor, binding at the myristoyl pocket of the BCR-ABL1 protein and locking it into an inactive conformation. … More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein[L38995] which serves as a driver of CML proliferation in most patients with the disease.

  2. Drug

    Polymyxin B

    go.drugbank.com/drugs/DB00781
    ApprovedInvestigationalVet approved

    It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of _Pseudomonas aeruginosa_[FDA Label].

    Mixtures: CVS First Aid Kit, 4231First Aid Kit
  3. Drug

    Dorzolamide

    go.drugbank.com/drugs/DB00869
    ApprovedInvestigational

    [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.

    Mixtures: Mint-dorzolamide/timolol
  4. Drug

    Sodium phosphate, monobasic

    go.drugbank.com/drugs/DB09449
    ApprovedInvestigational

    It usually results in a bowel movement after 30 minutes to 6 hours.

    Mixtures: Elo-Mel basis mit Glucose - Infusionslösung, Anticoagulant Cit Phos Dex Adenine Sol USP
  5. Drug

    Ciglitazone

    go.drugbank.com/drugs/DB09201
    Experimental

    Ciglitazone increases adipogenesis, decreases differentiation and angiogenesis in human umbilical vein endothelial cell (HUVEC), and osteoblastogenesis in human mesenchymal stem cells. … It is also an anti-hyperglycemic agent in the ob/ob murine model in vivo.

  6. Drug

    Cynodon dactylon pollen

    go.drugbank.com/drugs/DB10351
    Approved

    It can be cutaneously, intradermally and subcutaneously administered to initiate an immune response in case of an allergic reaction.

    Mixtures: 3 Grass Mix, 8 Southern Grass Mix
  7. Drug

    Avelumab

    go.drugbank.com/drugs/DB11945
    ApprovedInvestigational

    It is used in the treatment of Merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma. … [A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126] and Health Canada,[L48171] respectively.

  8. Drug

    Polyvinyl alcohol

    go.drugbank.com/drugs/DB11060
    Approved

    It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing.

    Mixtures: Premier Value Eye Drops Mt
  9. Drug

    Iodixanol

    go.drugbank.com/drugs/DB01249
    Approved

    Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the

    Mixtures: BL-C Kit
  10. Drug

    Alverine

    go.drugbank.com/drugs/DB01616
    ApprovedInvestigationalWithdrawn

    It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.