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Mevastatin
go.drugbank.com/drugs/DB06693ExperimentalThe compound was proposed to bind to the reductase enzyme and was named compactin. … Mevastatin is a pro-drug that is activated by <i>in vivo</i> hydrolysis of the lactone ring. It has served as one of the lead compounds for the development of the synthetic compounds used today.
IGN301
go.drugbank.com/drugs/DB05117ExperimentalIGN301 is a cancer vaccine based on an anti-idiotypic antibody which provokes an immune response to Lewis Y. … Lewis Y is a carbohydrate molecule expressed on the surface of tumor cells of epithelial origin (e.g. lung, intestinal, breast, prostate or ovarian cancers).
Afelimomab
go.drugbank.com/drugs/DB04956ExperimentalAfelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsCavia porcellus dander
go.drugbank.com/drugs/DB11019ApprovedCavia porcellus dander allergenic extract is used in allergenic testing.
Mixtures: Animal Allergens, Guinea Pig Hair and Dander, Animal Allergens, Guinea Pig Hair and DanderLoprazolam
go.drugbank.com/drugs/DB13643ExperimentalLoprazolam is an imidazobenzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. … It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent nocturnal awakenings.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesCeftiofur
go.drugbank.com/drugs/DB11485ExperimentalVet approvedIt is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported.
Aloglutamol
go.drugbank.com/drugs/DB13650InvestigationalAloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro.
Categories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacidsSapacitabine
go.drugbank.com/drugs/DB06365InvestigationalCategories: Nucleic Acids, Nucleotides, and NucleosidesTepoxalin
go.drugbank.com/drugs/DB11466ExperimentalVet approvedIt is primarily used to reduce inflammation and relief of pain caused by musculoskeletal disorders such as hip dysplasia and arthritis. … Tepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries.
Synonyms: 5-(p-Chlorophenyl)-1-(p-methoxyphenyl)-N-methylpyrazole-3-propionohydroxamic acidSifalimumab
go.drugbank.com/drugs/DB12773InvestigationalThe levels of interferon-alpha are elevated in many patients with active systemic lupus erythematosus (SLE, or lupus) and other autoimmune disorders, and may be associated with disease activity. … Sifalimumab may suppress the abnormal immune activity associated with lupus by binding to multiple interferon-alpha subtypes seen in the serum of lupus patients.
Categories: Amino Acids, Peptides, and Proteins