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Sifalimumab
go.drugbank.com/drugs/DB12773InvestigationalSifalimumab is a fully human monoclonal antibody targeting interferon-alpha.
Lefamulin
go.drugbank.com/drugs/DB12825ApprovedA pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus. … Lefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesButhionine sulfoximine
go.drugbank.com/drugs/DB12870InvestigationalButhionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Categories: Compounds used in a research, industrial, or household settingTrofosfamide
go.drugbank.com/drugs/DB12902InvestigationalTrofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMethylprednisone
go.drugbank.com/drugs/DB12952ApprovedInvestigationalWithdrawnMethylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCortivazol
go.drugbank.com/drugs/DB13003InvestigationalCortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersIrsogladine
go.drugbank.com/drugs/DB13056InvestigationalIrsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
Categories: Compounds used in a research, industrial, or household setting9-(N-methyl-L-isoleucine)-cyclosporin A
go.drugbank.com/drugs/DB13068Investigational9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse.
Delpazolid
go.drugbank.com/drugs/DB13077InvestigationalDelpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Talarozole
go.drugbank.com/drugs/DB13083InvestigationalTalarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
Categories: Cytochrome P-450 Enzyme Inhibitors