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Displaying results 6461 - 6470 of 10000 in total
  1. Drug

    Metrifonate

    go.drugbank.com/drugs/DB11473
    ExperimentalVet approved

    Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.

    Categories: Antiparasitic Products, Insecticides and Repellents, Compounds used in a research, industrial, or household setting
  2. Drug

    D-Glutamine

    go.drugbank.com/drugs/DB02174
    Experimental

    It is the principal carrier of nitrogen in the body and is an important energy source for many cells. … A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia.

    Categories: Amino Acids, Peptides, and Proteins
  3. Drug

    TAK-754

    go.drugbank.com/drugs/DB17850
    Investigational

    TAK-754 is an adeno-associated virus serotype 8 vector (AAV8) expressing B domain deleted codon optimized factor VIII. Developed by Takeda, it is being investigated for the treatment of hemophilia A.

  4. Indication

    Recurrent Cervical Cancer

    go.drugbank.com/conditions/DBCOND0028795
    Drugs: Bevacizumab · Cemiplimab · Pembrolizumab · Tisotumab vedotin · Vinorelbine
    Synonyms: Ca cervix recurrent
  5. Drug

    CYP-001

    go.drugbank.com/drugs/DB15739
    Investigational

    These cells are then able to differentiate into bone, cartilage, and adipose tissue. The MCA-derived MSCs can be obtained from induced pluripotent stem cells (iPSCs) and then expanded in media. … These cells have advantage over other MSCs because a large amount can be obtained from a single healthy blood donor, negating the risks from donor-and expansion dependent variability.

  6. Drug

    RGX-111

    go.drugbank.com/drugs/DB17632
    Investigational

    RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. … Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46666]

  7. Drug

    Panobacumab

    go.drugbank.com/drugs/DB15342
    Investigational

    Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa).

  8. Drug

    SYN-101

    go.drugbank.com/drugs/DB05958
    Experimental

    SYN101 is comprised of an immune cell specific antibody linked to an ALK5 inhibitor payload to selectively block TGF-b signalling in immune cells. … SYN-101 is an investigational antibody-drug conjugate developed for the treatment of cancer.

  9. Drug

    SAR445136

    go.drugbank.com/drugs/DB17708
    Investigational

    SAR445136 is an investigational zinc finger nuclease gene-edited cell therapy. … [A259063] It was formerly investigated for the treatment of beta-thalassemia, and it is currently being investigated for the treatment of sickle cell disease.[L46148]

  10. Drug

    Ostabolin-C

    go.drugbank.com/drugs/DB05536
    Investigational

    Ostabolin C was under investigation in clinical trial NCT00787358 (A Proof-of-Concept Study Investigating the Safety and Efficacy of ZT-031 on Hip Fracture Healing in Men and Postmenopausal Women (SHIFT

    Categories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone Antagonists