Search

Displaying results 651 - 660 of 10000 in total
  1. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine. … Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight.

    Categories: Drugs Used in DiabetesProducts: REPAGLINIDE EG
  2. Drug

    Antihemophilic factor human

    go.drugbank.com/drugs/DB13192
    ApprovedInvestigational

    The complex was developed by CSL Behring or Baxter Healthcare Corporation and approved in the 90s. … in the 1980s and 1990s [A31551, A32272].

    Mixtures: von Willebrand Factor/Coagulation Factor VIII Complex (Human), von Willebrand Factor/Coagulation Factor VIII Complex (Human)Products: FACTANE 500 IU/5 ML IV ENJ ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET, FACTANE 1000 IU/10 ML IV ENJ ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET
  3. Pathway

    Pyruvate Dehydrogenase Complex Deficiency

    smpdb.ca/view/SMP0000212
    Disease

    PDHA1 encodes the pyruvate dehydrogenase complex (PDC) a critical complex that converts pyruvate from glycolysis to acetyl CoA for the citric acid cycle. … Pyruvate dehydrogenase complex deficiency results from a mutation in the E1-alpha polypeptide gene (PDHA1).

    Drugs: Pyruvic acid · Biotin · Adenosine phosphate · Glutathione · NADH · ATP +13 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
  4. Pathway

    Mitochondrial Complex II Deficiency

    smpdb.ca/view/SMP0000548
    Disease

    Interestingly, complex II deficiency gene mutation carriers may be at an increased risk for certain cancers. … Because complex II is found in the mitochondria, CII deficiency is technically considered a mitochondrial disease.

    Drugs: Pyruvic acid · Biotin · Succinic acid · NADH · ATP · Magnesium cation +4 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
  5. Pathway

    Copper gluconate Drug Metabolism

    smpdb.ca/view/SMP0130548
    Metabolic

    Copper gluconate passes through the liver and is then excreted from the body mainly through the kidney. … Copper gluconate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Copper gluconate
  6. Drug

    Dexibuprofen

    go.drugbank.com/drugs/DB09213
    ApprovedWithdrawn

    Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability [A19259]. … It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties.

    Products: Eu-Med 200 mg Schmerztabletten
  7. Drug

    Hepatitis A Vaccine

    go.drugbank.com/drugs/DB10989
    ApprovedInvestigational

    [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]

    Categories: Complex MixturesProducts: VAQTA 50 E/1 ml Injektionssuspension in einer Fertigspritze, VAQTA K pro infantibus 25 E/0,5 ml Injektionssuspension in einer Fertigspritze
  8. Drug

    Valaciclovir

    go.drugbank.com/drugs/DB00577
    ApprovedInvestigational

    It was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. Valacyclovir is the L-valine ester of aciclovir. … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades.

    Products: VALACICLOVIR EG
  9. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    [L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. … [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.

    Synonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamineProducts: RIZATRIPTAN EG, RIZATRIPTAN LIN 1A PHA 5MG
  10. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    Approved

    Still docusate is available in over-the-counter products as a common laxative. … Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass [L1801]. Docusate can be orally or rectally administered.

    Mixtures: 2 In 1laxative Stool Softener and Stiulant Laxative, 2 In 1laxative Stool Softener and Stiulant LaxativeProducts: H E B Stool Softener laxative, Kao Tin