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Demplatin pegraglumer
go.drugbank.com/drugs/DB14807InvestigationalDemplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Synonyms: A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl linkagecisplatin is incorporated in polymeric micelles via polymer-metal complex formation withMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigationalMirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. … [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions.
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepineProducts: MIRTAZAPINA EG, MIRTAZAPINA EG STADAAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approvedA benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Mixtures: LO-BRUQUINSynonyms: O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamatePyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalPyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. … In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat dandruff and seborrheic dermatitis.
Synonyms: Pyridinethiol N-oxideProducts: L OCCITANE Anti-Dandruff Sensitive Scalp, Esika Men 2 En 1 Antidandruff Multi-actionMeropenem
go.drugbank.com/drugs/DB00760ApprovedInvestigationalIn August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI). … Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria.
Synonyms: (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acidProducts: MERONEM 1 GR IV ENJ. ICIN TOZ ICEREN FLAKON, 1 ADET, MERONEM 500 MG IV ENJ. ICIN TOZ ICEREN FLAKON, 1 ADETLidocaine
go.drugbank.com/drugs/DB00281ApprovedInvestigationalVet approvedRegardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis. … In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety
Mixtures: Venia Patch Premium Pain Patch, Venia Patch Premium Pain PatchSynonyms: 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamideLamotrigine
go.drugbank.com/drugs/DB00555ApprovedInvestigationalLamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. … It is approved for use in more than 30 countries.[A191350] Lamotrigine has relatively few side-effects and does not require laboratory monitoring.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: LAMOTRIGINA EG, Lamotrigine ERTolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedTolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm.
Synonyms: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamideProducts: TM-Tolnaftate LR, Ez ClearClopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigationalClopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. … [A180547] Clopidogrel was granted FDA approval on 17 November 1997.[L7213]
Mixtures: KLOGEL-A 75/75 MG KAPSUL, 30 ADET, KLOGEL-A 75/75 MG KAPSUL, 90 ADETProducts: CLOPIDOGREL EG, CLOPIDOGREL EG STADACarbidopa
go.drugbank.com/drugs/DB00190ApprovedInvestigationalCarbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. … therapy developed by Mayne Pharma in 1992.
Mixtures: LEVO/CA/EN 100/25/200 STD, LEVO/CA/EN 150/37.5/200STDCategories: Aromatic L-amino Acid Decarboxylase Inhibitors