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Displaying results 651 - 660 of 3732 in total
  1. Target

    Galanin receptor type 2

    go.drugbank.com/bio_entities/BE0011498
    TargetHumans

    Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). … The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i))

    Polypeptides: Galanin receptor type 2Function: galanin receptor activity
  2. Target

    Sigma intracellular receptor 2

    go.drugbank.com/bio_entities/BE0015084
    TargetHumans

    Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking

    Polypeptides: Sigma intracellular receptor 2Synonyms: Sigma2 receptor, Sigma-2 receptor
  3. Target

    Chemerin-like receptor 1

    go.drugbank.com/bio_entities/BE0019036
    TargetHumans

    Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1.

    Polypeptides: Chemerin-like receptor 1Synonyms: Chemokine-like receptor 1, G protein-coupled receptor DEZ
  4. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Sodium fluorophosphate

    go.drugbank.com/drugs/DB09484
    ApprovedInvestigational

    Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.

    Mixtures: Luster Premium White AM/PMProducts: Go Smile PM
  6. Drug

    Abiprubart

    go.drugbank.com/drugs/DB19333
    Investigational

    Abiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395

    Synonyms: 1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (115-212), hinge 1-12 S10>P, Immunoglobulin G4-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], humanized monoclonal antibody
  7. Target

    Endothelin receptor type B

    go.drugbank.com/bio_entities/BE0000043
    TargetHumans

    Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

    Polypeptides: Endothelin receptor type BSynonyms: Endothelin receptor non-selective type
  8. Target

    Muscarinic acetylcholine receptor M3

    go.drugbank.com/bio_entities/BE0000045
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M3
  9. Target

    Muscarinic acetylcholine receptor M1

    go.drugbank.com/bio_entities/BE0000092
    TargetHumans

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action

    Polypeptides: Muscarinic acetylcholine receptor M1Function: G protein-coupled acetylcholine receptor activity
  10. Target

    Cysteinyl leukotriene receptor 2

    go.drugbank.com/bio_entities/BE0000099
    TargetHumans

    Receptor for cysteinyl leukotrienes. The response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system.

    Polypeptides: Cysteinyl leukotriene receptor 2Synonyms: G protein-coupled receptor HG57, G protein-coupled receptor GPCR21