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Sodium bicarbonate
go.drugbank.com/drugs/DB01390ApprovedInvestigationalSodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Mixtures: E-Z-gas 2 Granules, E-Z-gas IIProducts: Life Q, DB Sodium Bicarbonate 8.4% w/v InjectionTemafloxacin
go.drugbank.com/drugs/DB01405ApprovedWithdrawnTemafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class. It was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reacti...
Categories: 4-Quinolones, Cytochrome P-450 SubstratesPranlukast
go.drugbank.com/drugs/DB01411InvestigationalPranlukast is a cysteinyl leukotriene receptor-1 antagonist.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsStepronin
go.drugbank.com/drugs/DB01423ExperimentalStrepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties.
Categories: Heterocyclic Compounds, 1-RingAminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnAminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. … The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942]
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: 4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazoloneAjmaline
go.drugbank.com/drugs/DB01426ApprovedWithdrawnAjmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very useful drug for acute intravenous treatments. … It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.
Categories: Antiarrhythmics, Class I, Heterocyclic Compounds, 2-RingSynonyms: (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo[3,2-b]quinolizine-8,13-diol3-Methylthiofentanyl
go.drugbank.com/drugs/DB01439ExperimentalIllicit3-Methyl-thiofentanyl is a [fentanyl] analog and an opioid analgesic that works by inducing central nervous system (CNS) depression.
Synonyms: 3-Methyl-thiofentanyl, 3-MethylthiofentanylBezitramide
go.drugbank.com/drugs/DB01459ApprovedIllicitWithdrawnBezitramide is a narcotic analgesic which was discovered in 1961, clinically tested around the 1970's [A14383], and marketed under the name Burgodin. … Bezitramide has never been FDA approved and is currently a schedule II drug.
Categories: Heterocyclic Compounds, 2-RingFencamfamin
go.drugbank.com/drugs/DB01463ApprovedIllicitWithdrawnFencamfamin (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant. … It is around half the potency of [dexamphetamine], and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose.
Desmethylprodine
go.drugbank.com/drugs/DB01478ExperimentalIllicitIt has been listed as a Schedule I controlled drug in the United States, and thus is not used clinically. It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. … Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-4-phenyl-4-piperidinol propionate, 1-Methyl-4-phenyl-4-propionoxypiperidine