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Benazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: CİBADREX 5/6,25 MG FİLM TABLET, 28 ADET, CİBADREX 10/12,5 MG FİLM TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-RingPerazine
go.drugbank.com/drugs/DB12710ApprovedWithdrawnPerazine has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Categories: Heterocyclic Compounds, 3-RingProducts: PERAZIN-NEURAX 25 MG, PERAZIN-NEURAX 100 MGDesvenlafaxine
go.drugbank.com/drugs/DB06700ApprovedInvestigationalDesvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of [venlafaxine]. … [L6016,A261271] MDD is a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and 12.8% in Europe.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: O-desmethylvenlafaxineSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: L-DeprenalinMethyl aminolevulinate
go.drugbank.com/drugs/DB00992ApprovedInvestigationalMethyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Synonyms: methyl 5-aminolevulinate, methyl δ-aminolevulinateProducts: METVIX® CREMA 160 MG/G, Luxerm 160 mg/g CremeGliquidone
go.drugbank.com/drugs/DB01251ApprovedGliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: GLURENOR 30 MG TABLETTEN, Glurenorm 30 mg - TablettenVasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigationalthrough V<sub>1</sub> and V<sub>2</sub> cellular receptors. … [A228013] It is currently marketed under the trademark VASOSTRICT® by PAR Pharmaceuticals.[L31413]
Products: Empesin 40 I.E./2 ml Konzentrat zur Herstellung einer Infusionslösung, VASOPRESSIN INJECTION USP 20 u/mlColloidal oatmeal
go.drugbank.com/drugs/DB11286ApprovedNutraceuticalIt is available in topical products as a skin soothing agent. … Colloidal oatmeal is a FDA-approved skin protectant that temporarily protects and helps relieve minor skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites.
Mixtures: Pediadermics Eczema 3, 5% Oat Facial CleanserProducts: 3-In-1 Relief CVS, ZO MEDICAL 3-STEP PEEL Kit3-oxo-5-alpha-steroid 4-dehydrogenase 1
go.drugbank.com/bio_entities/BE0000539TargetEnzymeHumansCatalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 1Function: 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activityNuclear receptor subfamily 4 group A member 3
go.drugbank.com/bio_entities/BE0008998TargetHumansInduces gene expression by binding as monomers to the NR4A1 response element (NBRE) 5'-AAAAGGTCA-3' site and as homodimers to the Nur response element (NurRE) site in the promoter of their regulated target
Polypeptides: Nuclear receptor subfamily 4 group A member 3