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Prasugrel
go.drugbank.com/drugs/DB06209ApprovedInvestigationalSimilar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. … Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: PRASUGREL BETA 5 MG FTA, Prasulan 5 mg-FilmtablettenRoxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalRoxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: Ernevod 20 mg Film Kaplı Tablet (12 adet), EVRENZO 20 MG FİLM KAPLI TABLET, 12 ADETTrospium
go.drugbank.com/drugs/DB00209ApprovedInvestigationalTrospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: TROSBIO® 30 MG, TROSBIO® 15 MGRemdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigationalSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia … [L18438] Remdesivir was also approved by the European Commission on July 3, 2020.
Categories: Heterocyclic Compounds, 2-Ring, SARS-CoV-2 Nucleotide Analog RNA Polymerase InhibitorProducts: VEKLURY 100 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET, VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
go.drugbank.com/bio_entities/BE0001661TargetEscherichia coli (strain K12)Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Polypeptides: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseSynonyms: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
go.drugbank.com/bio_entities/BE0001839TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Polypeptides: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseSynonyms: 4-diphosphocytidyl-2C-methyl-D-erythritol synthasealpha-Tocopherol succinate
go.drugbank.com/drugs/DB14001ApprovedNutraceuticalVet approved, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males … The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months
Synonyms: Vitamin E succinate, Vitamin E hemisuccinateMixtures: V & M Vitamin and Mineral Supplement, Formula Ma-vitamin E & Zinc Tab4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
go.drugbank.com/bio_entities/BE0001574TargetShigella flexneriCatalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Polypeptides: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinaseSynonyms: 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
go.drugbank.com/bio_entities/BE0003931TargetHumansSynthesis and degradation of fructose 2,6-bisphosphate
Polypeptides: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4Synonyms: 6PF-2-K/Fru-2,6-P2ase 4, PFK/FBPase 4Dehydrogenase/reductase SDR family member 4-like 2
go.drugbank.com/bio_entities/BE0004192TargetHumansProbable oxidoreductase
Polypeptides: Dehydrogenase/reductase SDR family member 4-like 2Synonyms: Short chain dehydrogenase/reductase family 25C member 3