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MD-0727
go.drugbank.com/drugs/DB05948InvestigationalMD-0727 is a novel, potent cholesterol absorption inhibitor (CAI) under investigation for the treatment of hypercholesterolemia (high cholesterol.
PNT001
go.drugbank.com/drugs/DB18375InvestigationalPNT001 is a humanized IgG4 S228P monoclonal antibody targeting the cis conformation of the phosphorylated Thr231-Pro232 motif in tau.
NN344
go.drugbank.com/drugs/DB05115ExperimentalThe product is intended for basal insulin treatment of diabetes mellitus.
Affitope AD01
go.drugbank.com/drugs/DB06086InvestigationalAffitope AD01 is an investigational drug developed for immunization to treat Alzheimer's Disease.
Fluorfenidine F-18
go.drugbank.com/drugs/DB19557ExperimentalThe usage of the INN stem '-nidine' in the name indicates that Fluorfenidine F-18 is a a2 adrenoreceptor agonist. Fluorfenidine F-18 has a monoisotopic molecular weight of 382.07 Da.
FRAX597
go.drugbank.com/drugs/DB31734ExperimentalFRAX597 is a small molecule drug that inhibits the p21-activated kinases (PAKs).[A274673, A274678]
TM5614
go.drugbank.com/drugs/DB16516InvestigationalTM5614 inhibition of PAI-1, specifically, downregulates PCSK9 at the transcriptional level[A228793].
ISIS 325568
go.drugbank.com/drugs/DB06099InvestigationalISIS 325568 is a generation 2.2 antisense drug that targets the glucagon receptor (GCGR).
Opiranserin
go.drugbank.com/drugs/DB16271InvestigationalOpiranserin is under investigation in clinical trial NCT03997838 (Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-operative Pain Following Abdominoplasty).