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Pentoxyverine
go.drugbank.com/drugs/DB11186ApprovedWithdrawnPentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate. … Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and local anesthetic properties.
Mixtures: GAYABEN 150 ML SURUP, V-cofProducts: PENTOXYVERIN AL 1.35 MG/ML, Mucomat Hustenstiller 2,13 mg/ml Lösung zum EinnehmenClonazepam
go.drugbank.com/drugs/DB01068ApprovedIllicitInvestigational[FDA Label][A175438,A175441,L5572,F3763,F3787,F3796] Since being first patented in 1960 and then released for sale from Roche in the US in 1975,[T469,T472] clonazepam has experienced a storied history … A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 InhibitorsSynonyms: 5-(2-chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one, 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-oneTenofovir disoproxil
go.drugbank.com/drugs/DB00300ApprovedInvestigationalThis drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label]. … Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase
Mixtures: EMTRIFOVIR® 300/200 MG TABLETAS RECUBIERTA., TENOHOPE E (EMTRICITABINE 200 MG & TENOFOVIR DISOPROXIL FUMARATE 300 MG TABLETS)Categories: P-glycoprotein inhibitors, P-glycoprotein substratesOlea europaea leaf
go.drugbank.com/drugs/DB14745InvestigationalMixtures: LA FEMME V Feminine CleanserSynonyms: Olea europaea leaf, Olea europaea (olive) leafColchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961. … [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602]
Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: Colctab 1 mg Tabletten, Colchanova 1 mg TablettenMethylphenidate
go.drugbank.com/drugs/DB00422ApprovedInvestigational[A177550] Clinical findings have shown that children with ADHD have an abnormality in the dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene that may be at least … Water then permeates through the membrane into the tablet core where the osmotically active polymer excipients expand, allowing methylphenidate to release slowly through the orifice over a period of 6-
Mixtures: MEDIKINET MR, MEDIKINET MRCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingAcylcarnitine non-6-enoylcarnitine
smpdb.ca/view/SMP0123419Metabolicnon-6-enoylcarnitine is an acylcarnitine. … Once in the matrix, non-6-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form non-6-enoyl-CoA and L-carnitine. non-6
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine Dodec-6-enedioylcarnitine
smpdb.ca/view/SMP0124022MetabolicDodec-6-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, dodec-6-enedioyl-CoA reacts with L-carnitine to form dodec-6-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine octadec-6-enoylcarnitine
smpdb.ca/view/SMP0124320Metabolicoctadec-6-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, octadec-6-enoyl-CoA reacts with L-carnitine to form octadec-6-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 morePentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Categories: P-glycoprotein substratesProducts: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/ml