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Displaying results 671 - 680 of 10000 in total
  1. Indication

    Mucopolysaccharidosis Type I (MPS I)

    go.drugbank.com/conditions/DBCOND0065667
    Drugs: Laronidase
    Synonyms: MPS 1-S - Mucopolysaccharidosis type I-S, Mucopolysaccharidosis type I-S
  2. Drug

    Oxcarbazepine

    go.drugbank.com/drugs/DB00776
    ApprovedInvestigational

    - a pro-drug of the more active (S)-enantiomer is also marketed as a separate anti-epileptic under the name [eslicarbazepine]. … [L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood

    Categories: P-glycoprotein inducers, P-glycoprotein substratesSynonyms: 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
  3. Drug

    Oxymetazoline

    go.drugbank.com/drugs/DB00935
    ApprovedInvestigational

    Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors. … [L15062] As an effective decongestant, oxymetazoline is available in over-the-counter intranasal sprays used to relieve nasal and sinus congestion caused by a wide variety of conditions, such as common

    Mixtures: N-S-4Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  4. Drug

    Benzethonium

    go.drugbank.com/drugs/DB11125
    Approved

    There is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304]. … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments.

    Products: CLEAR S Suds, First Mark Foaming Hand Cleaner
  5. Drug

    Sodium chlorite

    go.drugbank.com/drugs/DB13210
    Investigational

    Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413]. … Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S.

    Products: Qve - S, V Doctor pure chlorine dioxide
  6. Drug

    Polyethylene glycol

    go.drugbank.com/drugs/DB09287
    ApprovedInvestigationalVet approved

    PEGs have a long history of gastroenterology: PEG 3350 is a common over-the-counter osmotic laxative used to relieve occasional constipation. … Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.

    Mixtures: Gavilyte-N, DAXTELY FCategories: P-glycoprotein inhibitors, Compounds used in a research, industrial, or household setting
  7. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … such as bipolar disorder, retina protection, and wound healing.

    Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapCategories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  8. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.

    Mixtures: Entre-S, Colcol-SCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Adrenergic alpha-1 Receptor Agonists
  9. Drug

    Ubidecarenone

    go.drugbank.com/drugs/DB09270
    ApprovedInvestigationalNutraceutical

    [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease. … It is fundamental for cells that have a high metabolic demand.

    Mixtures: Nature"s Gift CoQ10 Plus, Kordel"s CoQ10 75MG + Omega 3-6 CapsulesCategories: P-glycoprotein substrates
  10. Drug

    Bacitracin

    go.drugbank.com/drugs/DB00626
    ApprovedInvestigationalVet approved

    Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. … [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy.

    Mixtures: Band-aid-S-1, S-Oint TRIPLE ANTIBIOTICSynonyms: Bacitracin A