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Minoxidil
go.drugbank.com/drugs/DB00350ApprovedInvestigationalA potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Synonyms: 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide, 2,4-Diamino-6-piperidinopyrimidine 3-oxideMixtures: MINOXIDIL 7% / NIACINAMIDE 4% s, FluMisch 5% MinoxidilMegestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approved17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. … As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Synonyms: 17α-Acetoxy-6-dehydro-6-methylprogesterone, 17alpha-Acetoxy-6-dehydro-6-methylprogesteroneCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesChlorzoxazone
go.drugbank.com/drugs/DB00356ApprovedA centrally acting central muscle relaxant with sedative properties.
Synonyms: 5-chloro-2-benzoxazolol, 5-chloro-2-benzoxazolinoneInternational brands: Remular-SSapropterin
go.drugbank.com/drugs/DB00360ApprovedInvestigationaltryptophan to 5-hydroxytryptophan via tryptophan hydroxylase. … Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide.
Synonyms: 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone, (−)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinoneCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-RingClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigationalClozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. … [L905] Due to its severe adverse effects profile, clozapine is only available through a restricted program under a Risk Evaluation Mitigation Strategy (REMS) called the Clozapine REMS Program.[L905]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: SIZOPIN® TABLETAS, ZAPEN® TABLETAS 25 MGLevonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigationalA subdermal implant of levonorgestrel that slowly releases the hormone over a long-term period is also available. … [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD.
Synonyms: 13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one, (-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-oneMixtures: ไมโครเลนิน 30 ท.ว, ไมโครเลนิน 50 ท.ว.Norepinephrine
go.drugbank.com/drugs/DB00368ApprovedInvestigationalIt is also found in plants and is used pharmacologically as a sympathomimetic. … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter.
Synonyms: (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol, 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediolMixtures: XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUSCidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigationalCidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] I...
Synonyms: ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid, (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acidCategories: Heterocyclic Compounds, 1-RingMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine, 6-AzamianserinCategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor AntagonistsThiethylperazine
go.drugbank.com/drugs/DB00372ApprovedInvestigationalWithdrawnA dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins.
Synonyms: 2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazineCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-Ring