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JSM 6427
go.drugbank.com/drugs/DB06139InvestigationalJSM 6427 is the first small molecule alpha5beta1 integrin receptor antagonist of its kind to be developed. It has been biologically validated for therapeutic use in the prevention and treatment of wet AMD, the leading cause of blindness ...
Aminoimidazole carboxamide
go.drugbank.com/drugs/DB06143InvestigationalSynonyms: 5-Aminoimidazol-4-carboxamide, 5-Aminoimidazole-4-carboxamideCategories: Heterocyclic Compounds, 1-RingSertindole
go.drugbank.com/drugs/DB06144ApprovedWithdrawnSertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. … It is a phenylindole derivative used in the treatment of schizophrenia.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-oneSulfathiazole
go.drugbank.com/drugs/DB06147ApprovedVet approvedWithdrawnSulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered.
Categories: Heterocyclic Compounds, 1-RingSynonyms: N(1)-2-Thiazolylsulfanilamide, 4-Amino-N-2-thiazolylbenzenesulfonamideMianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnA tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 3-RingSynonyms: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepineAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigational[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.
Mixtures: N-ACETILCISTEÍNA 2 G + GUAYACOLATO DE GLICERILO 2 G JARABE, AMINOPLASMAL-5% E INFUSIONCategories: Compounds used in a research, industrial, or household settingNylidrin
go.drugbank.com/drugs/DB06152ApprovedWithdrawnNylidrin is a peripheral vasodilator.
Categories: 2-Amino-1-Phenylethanol Derivatives, Cytochrome P-450 SubstratesRimonabant
go.drugbank.com/drugs/DB06155ApprovedWithdrawnThis decision was made after a U.S. advisory panel recommended the medicine not be approved because it may increase suicidal thinking and depression.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: ACOMPLIA ® COMPRIMIDOS RECUBIERTOS20 MGIstaroxime
go.drugbank.com/drugs/DB06157InvestigationalSynonyms: (E,Z)-Istaroxime, 3-((2-Aminoethoxy)imino)-5alpha-androstan-6,17-dioneGarenoxacin
go.drugbank.com/drugs/DB06160ExperimentalGarenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-Ring