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Rose bengal
go.drugbank.com/drugs/DB11182ApprovedInvestigationalRose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. … A direct cytotoxic effect of Rose bengal on microorganisms and cancer cells has been observed, questioning its potential antitumor actions via intralesional injections.
Categories: Heterocyclic Compounds, 3-Ring, Compounds used in a research, industrial, or household settingLevomefolic acid
go.drugbank.com/drugs/DB11256ApprovedIt is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the stability required for use as a supplement [A19276]. … Levomefolate is approved as a food additive and is designated a GRAS (generally regarded as safe) compound [L773].
Mixtures: L-Methyl-B6-B12, L-Methyl MCCategories: Vitamin B Complex, Heterocyclic Compounds, 2-RingDihydroergocornine
go.drugbank.com/drugs/DB11273Approved[A32965] Dihydroergocornine presents a formula of 9,10 alpha-dihydro-12'-hydroxy-2',5'alpha-bis(1-methylethyl)-ergotaman-3',6',18-trione.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDipyrithione
go.drugbank.com/drugs/DB11327Approved[L2611] It is currently used as a pesticide, and not used in any FDA approved drug products. … Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff shampoo, but is no longer available.
Categories: Heterocyclic Compounds, 1-RingGuaiacol
go.drugbank.com/drugs/DB11359ApprovedGuaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin.
Mixtures: NOKTOS ® ADULTOS JARABE.Synonyms: 1-hydroxy-2-methoxybenzene, 2-methoxyl-4-vinylphenolDanofloxacin
go.drugbank.com/drugs/DB11393ExperimentalVet approvedDanofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingMedetomidine
go.drugbank.com/drugs/DB11428ExperimentalVet approvedMedetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. … Medetomidine is an intravenously available alpha-2 adrenergic agonist. The drug has been developed by Orion Pharma.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsSynonyms: (±)-4-(α,2,3-trimethylbenzyl)imidazoleOleandomycin
go.drugbank.com/drugs/DB11442ExperimentalVet approvedOleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of _Streptomyces antibioticus_.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsCeftiofur
go.drugbank.com/drugs/DB11485ExperimentalVet approvedE. coli strains resistant to ceftiofur have been reported. … Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine.
Categories: Heterocyclic Compounds, 2-RingNalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedNalorphine is a mixed opioid agonist–antagonist. … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Categories: Heterocyclic Compounds with 4 or More Rings