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JUR-003
go.drugbank.com/drugs/DB33972ExperimentalJUR-003 is a small molecule drug. JUR-003 is under investigation in clinical trial NCT07824349 (JUR-003 in Adult Patients With Metastatic Prostate Cancer).
Pralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedPralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after...
Synonyms: 2-PAMCategories: Compounds used in a research, industrial, or household settingHetacillin
go.drugbank.com/drugs/DB00739ApprovedVet approvedWithdrawnHetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. … Hetacillin has been withdrawn from the market since it has been discovered that it has no therapeutic advantage compared to non-ester derivatives like ampicillin.
Synonyms: (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6β-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]penicillanic acidCategories: Heterocyclic Compounds, 2-RingHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] … [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Synonyms: Kendall's compound F, Reichstein's substance MInternational brands: Polcort H, Preparation H Hydrocortisone CreamDeferoxamine
go.drugbank.com/drugs/DB00746ApprovedInvestigationalIt forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Synonyms: Deferrioxamine BCategories: Compounds used in a research, industrial, or household settingCarbinoxamine
go.drugbank.com/drugs/DB00748ApprovedCarbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. … This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.
Synonyms: 2-(p-chloro-α-(2-(dimethylamino)ethoxy)benzyl)pyridine, {2-[(4-Chloro-phenyl)-pyridin-2-yl-methoxy]-ethyl}-dimethyl-amineMixtures: PHILDEX 2Etodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedEtodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties.
Synonyms: (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acidMixtures: NuDroxiPAK E-400, ETOTIO 400 MG/8 MG FILM TABLET, 20 ADETEthotoin
go.drugbank.com/drugs/DB00754ApprovedEthotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression.
Synonyms: (±)-3-ethyl-5-phenylhydantoin, 3-ethyl-5-phenylhydantoinCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersDolasetron
go.drugbank.com/drugs/DB00757ApprovedInvestigationalDolasetron is a highly specific and selective serotonin 5-HT3 receptor antagonist.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingTetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnTetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. … The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml.
Synonyms: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors