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Displaying results 6911 - 6920 of 10000 in total
  1. Target

    Chitotriosidase-1

    go.drugbank.com/bio_entities/BE0001058
    TargetEnzymeHumans

    Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity

    Polypeptides: Chitotriosidase-1Synonyms: Chitinase-1
  2. Target

    Stromelysin-1

    go.drugbank.com/bio_entities/BE0001116
    TargetHumans

    In addition, plays a role in immune response and possesses antiviral activity against various viruses such as vesicular stomatitis virus, influenza A virus (H1N1) and human herpes virus 1 (PubMed:35940311

    Polypeptides: Stromelysin-1Synonyms: SL-1, Transin-1
  3. Target

    Transketolase 1

    go.drugbank.com/bio_entities/BE0003276
    TargetEnzymeEscherichia coli (strain K12)

    Thus, catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate.

    Polypeptides: Transketolase 1Synonyms: TK 1
  4. Target

    Axin-1

    go.drugbank.com/bio_entities/BE0003316
    TargetHumans

    Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling (PubMed:12192039, PubMed:27098453, PubMed:28829046). Controls dorsoventral p...

    Polypeptides: Axin-1Synonyms: Axis inhibition protein 1
  5. Target

    Pannexin-1

    go.drugbank.com/bio_entities/BE0003719
    TargetTransporterHumans

    Ion channel involved in a variety of physiological functions such as blood pressure regulation, apoptotic cell clearance and oogenesis (PubMed:15304325, PubMed:16908669, PubMed:20829356, PubMed:20944749, PubMed:30918116). Forms anion-sel...

    Polypeptides: Pannexin-1
  6. Target

    Phosphoglucomutase-1

    go.drugbank.com/bio_entities/BE0004461
    TargetEnzymeHumans

    Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate (PubMed:15378030, PubMed:25288802).

    Polypeptides: Phosphoglucomutase-1Synonyms: PGM 1, Glucose phosphomutase 1
  7. Target

    Synapsin-1

    go.drugbank.com/bio_entities/BE0004488
    TargetHumans

    Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal (PubMed:21441247,...

    Polypeptides: Synapsin-1
  8. Target

    Galectin-1

    go.drugbank.com/bio_entities/BE0004493
    TargetHumans

    Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylati...

    Polypeptides: Galectin-1Synonyms: Gal-1, S-Lac lectin 1
  9. Target

    Lipocalin-1

    go.drugbank.com/bio_entities/BE0005828
    TargetHumans

    Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocycl...

    Polypeptides: Lipocalin-1
  10. Target

    Copine-1

    go.drugbank.com/bio_entities/BE0009002
    TargetHumans

    Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes (PubMed:14674885). Involved in the TNF receptor signaling pathway in a calcium-dependent manner (PubMed:14674885). Exhibits calc...

    Polypeptides: Copine-1