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Atenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … [A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality
Mixtures: PLENACOR D, PRETENOL C 50 TABLETCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsPimecrolimus
go.drugbank.com/drugs/DB00337ApprovedInvestigationalIt is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ELIDEL CREAM 1% w/w, ELIDEL® 1% CREMAMinoxidil
go.drugbank.com/drugs/DB00350ApprovedInvestigationalA potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Mixtures: MINOXIDIL 7% / NIACINAMIDE 4% s, FluMisch 5% MinoxidilCategories: Heterocyclic Compounds, 1-RingMegestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approved17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. … As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 17α-Acetoxy-6-dehydro-6-methylprogesterone, 17alpha-Acetoxy-6-dehydro-6-methylprogesteroneChlorzoxazone
go.drugbank.com/drugs/DB00356ApprovedA centrally acting central muscle relaxant with sedative properties.
Mixtures: Parafon Forte C8 W Codeine TabCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigationalClozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. … [L905] Due to its severe adverse effects profile, clozapine is only available through a restricted program under a Risk Evaluation Mitigation Strategy (REMS) called the Clozapine REMS Program.[L905]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: SIZOPIN® TABLETAS, ZAPEN® TABLETAS 25 MGLevonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigationalA subdermal implant of levonorgestrel that slowly releases the hormone over a long-term period is also available. … [A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD.
Mixtures: ไมโครเลนิน 30 ท.ว, ไมโครเลนิน 50 ท.ว.Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNorepinephrine
go.drugbank.com/drugs/DB00368ApprovedInvestigationalIt is also found in plants and is used pharmacologically as a sympathomimetic. … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter.
Mixtures: XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUSCategories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsCarbimazole
go.drugbank.com/drugs/DB00389ApprovedAn imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylateSulpiride
go.drugbank.com/drugs/DB00391ApprovedWithdrawn[A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses.
Mixtures: NEUPAX DUO-SCategories: MATE 1 Substrates, MATE 2 Substrates