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Drinabant
go.drugbank.com/drugs/DB05750InvestigationalAVE-1625 is an oral selective and potent antagonist of cannabinoid 1 (CB1) receptors having the same mechanism of action as rimonabant.
Ertiprotafib
go.drugbank.com/drugs/DB06521ExperimentalIn insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improved glycemic excursion during an oral glucose tolerance test.
Brasofensine
go.drugbank.com/drugs/DB04857ExperimentalBrasofensine is an orally administered dopamine reuptake inhibitor being developed for the treatment of Parkinson's Disease. Phase I/II trials for brasofensine have been completed in the U.K.
Inhibitor of P38 Kinase
go.drugbank.com/drugs/DB01953ExperimentalThese are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to form 2,3-benzopyrrole. This drug is known to target mitogen-activated protein kinase 14.
Felezonexor
go.drugbank.com/drugs/DB21067InvestigationalFelezonexor has a monoisotopic molecular weight of 419.12 Da.
Edaxeterkib
go.drugbank.com/drugs/DB21490InvestigationalEdaxeterkib has a monoisotopic molecular weight of 469.22 Da.
Telenzepine
go.drugbank.com/drugs/DB19508InvestigationalTelenzepine has a monoisotopic molecular weight of 370.15 Da.
Setileuton
go.drugbank.com/drugs/DB19550InvestigationalSetileuton has a monoisotopic molecular weight of 463.12 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates